Pulegone

Pulegone

SCHEMBL8196865

CC(C)=C1CC[C@@H](C)CC1=O.CCCCCCC

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.36
ALDH1A1 P00352 3/20 0.34
NPC1 O15118 2/20 0.34
HPGD P15428 2/20 0.34
RAB9A P51151 2/20 0.34
LIPE Q05469 1/20 0.33
KDM4E B2RXH2 1/20 0.33
PPARG P37231 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
FAAH O00519 1/20 0.33
MGLL Q99685 1/20 0.33
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C19 P33261 1/20 0.32
RECQL P46063 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
PTPN1 P18031 1/20 0.32
CDC25B P30305 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Tridecanone SCHEMBL27673021 0.91 PRKCA (0.35)
Pulegone SCHEMBL3064832 0.88 PTPN2 (0.35) ALDH1A1NPC1HPGDRAB9AKDM4E
Pulegone SCHEMBL9292430 0.86 PTPN2 (0.38) ALDH1A1NPC1HPGDRAB9AKDM4E
Pulegone SCHEMBL8836768 0.86 ALDH1A1 (0.34) ALDH1A1NPC1HPGDRAB9AKDM4E
Pulegone SCHEMBL27243547 0.86 ALDH1A1 (0.34) ALDH1A1NPC1HPGDRAB9AKDM4E
Pulegone SCHEMBL6517913 0.75
Pulegone SCHEMBL17963980 0.72 TLR4 (0.31) NPC1L3MBTL1
SCHEMBL27902418 0.70 TLR4 (0.33) ALDH1A1NPC1HPGDRAB9AKDM4E
SCHEMBL9292431 0.67 PTPN2 (0.32) PTPN1
SCHEMBL9075333 0.65 CRBN (0.34) ALDH1A1HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6121234-A ORALLY COADMINISTERING TO MAMMAL PHARMACEUTICAL COMPOUND AND ESSENTIAL OIL AVMAX, INC. (US) 2000-09-19 US disclosed
US-5916566-A Use of benzoin gum to inhibit P-glycoprotein-mediated resistance of pharmaceutical compounds AVMAX, INC. (US) 1999-06-29 US disclosed
US-5716928-A ADMINISTERING DRUG CONCURRENTLY WITH ESSENTIAL OIL AVMAX, INC. (US) 1998-02-10 US disclosed