Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 15/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5806927 | 0.86 | ROCK2 (0.34) | ROCK2 | |
| SCHEMBL5806941 | 0.85 | POLB (0.39) | P2RX3ROCK2 | |
| SCHEMBL5811828 | 0.85 | ROCK2 (0.32) | ROCK2 | |
| SCHEMBL5808116 | 0.84 | FPR2 (0.38) | — | |
| SCHEMBL5820989 | 0.84 | CYP1A2 (0.40) | — | |
| SCHEMBL5822134 | 0.84 | ROCK2 (0.32) | ROCK2 | |
| SCHEMBL5806875 | 0.83 | EGLN1 (0.35) | ROCK2 | |
| SCHEMBL5811632 | 0.82 | EGLN1 (0.33) | ROCK2 | |
| SCHEMBL5807940 | 0.82 | EGLN1 (0.33) | ROCK2 | |
| SCHEMBL5809821 | 0.81 | EGLN1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006106416-A1 | PYRIDIL-LACTAMS AND THEIR USE 5 -HTl RECEPTORS LIGAN | PFIZER PRODUCTS INC. (US) | 2006-10-12 | — | — | WO | claimed |
| WO-2006106416-A1 | PYRIDIL-LACTAMS AND THEIR USE 5 -HTl RECEPTORS LIGAN | PFIZER PRODUCTS INC. (US) | 2006-10-12 | — | — | WO | disclosed |