Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | GRM8 | O00222 | 4/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.43 |
| ▸ | ACP3 | P15309 | 1/20 | 0.43 |
| ▸ | GRM6 | O15303 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2997453 | 0.84 | CA2 (0.48) | CA2CA5AKMT2AL3MBTL1MEN1 | |
| SCHEMBL28769100 | 0.81 | CA2 (0.50) | CA2CA5AKMT2AL3MBTL1MEN1 | |
| SCHEMBL9550605 | 0.77 | KMT2A (0.51) | CA2CA5AKMT2AL3MBTL1MEN1 | |
| SCHEMBL9062716 | 0.75 | KMT2A (0.49) | CA2CA5AKMT2AL3MBTL1MEN1 | |
| SCHEMBL9299523 | 0.75 | GRM8 (0.51) | KMT2AL3MBTL1MEN1HPGDGRM8 | |
| SCHEMBL29866906 | 0.75 | L3MBTL1 (0.58) | CA2KMT2AL3MBTL1MEN1HPGD | |
| SCHEMBL21200058 | 0.75 | L3MBTL1 (0.58) | CA2KMT2AL3MBTL1MEN1HPGD | |
| SCHEMBL11786819 | 0.74 | KMT2A (0.45) | CA2CA5AKMT2AL3MBTL1MEN1 | |
| SCHEMBL11452596 | 0.73 | L3MBTL1 (0.59) | KMT2AL3MBTL1MEN1HPGDGRM8 | |
| SCHEMBL27830078 | 0.73 | HTT (0.51) | L3MBTL1GRM8GRM4ACP3GRM6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006129100-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2006-12-07 | — | — | WO | disclosed |