Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5819856 | 0.88 | MAPT (0.53) | PTPN11MEN1NR1I2LMNACHRM2 | |
| SCHEMBL5820306 | 0.83 | LMNA (0.63) | PTPN11MEN1NR1I2LMNACHRM2 | |
| SCHEMBL8142503 | 0.83 | LMNA (0.63) | PTPN11MEN1NR1I2LMNACHRM2 | |
| SCHEMBL5820347 | 0.83 | LMNA (0.63) | PTPN11MEN1NR1I2LMNACHRM2 | |
| SCHEMBL8575442 | 0.81 | MAPT (0.57) | POLBMEN1LMNAMAPTSLC6A3 | |
| SCHEMBL5819940 | 0.80 | TP53 (0.60) | NR1I2LMNACHRM2CYP3A4ADRA2A | |
| SCHEMBL2454085 | 0.80 | PPARG (0.56) | CYSLTR2CYSLTR1THRATHRBPTPN11 | |
| SCHEMBL5816099 | 0.80 | TP53 (0.60) | NR1I2LMNACHRM2CYP3A4ADRA2A | |
| SCHEMBL5819931 | 0.80 | TP53 (0.60) | NR1I2LMNACHRM2CYP3A4ADRA2A | |
| SCHEMBL4365539 | 0.79 | LMNA (0.54) | PTPN11MEN1NR1I2LMNACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006132588-A1 | METHOD FOR THE PURIFICATION OF SYNTHETIC OLIGONUCLEOTIDES CONTAINING ONE OR SEVERAL LABELS | QUIATECH AB (SE) | 2006-12-14 | — | — | WO | disclosed |