Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | NPC1 | O15118 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | RAB9A | P51151 | 6/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | RAD52 | P43351 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | PDE4A | P27815 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30205105 | 0.83 | NPC1 (0.81) | MAPTNPC1ALDH1A1RAB9AHPGD | |
| SCHEMBL3224251 | 0.83 | NPC1 (0.81) | MAPTNPC1ALDH1A1RAB9AHPGD | |
| SCHEMBL9253579 | 0.81 | NPC1 (0.50) | NPC1RAB9AHPGDSMN1; SMN2LMNA | |
| SCHEMBL5819937 | 0.81 | CYSLTR2 (0.46) | MAPTLMNAKMT2AMEN1SLC6A3 | |
| SCHEMBL10739836 | 0.79 | NPC1 (0.65) | MAPTNPC1ALDH1A1RAB9AHPGD | |
| SCHEMBL9009439 | 0.79 | ALDH1A1 (0.47) | MAPTNPC1ALDH1A1RAB9AHPGD | |
| SCHEMBL9101 | 0.79 | RAB9A (0.58) | MAPTNPC1ALDH1A1RAB9AHPGD | |
| SCHEMBL30307041 | 0.78 | NPC1 (0.56) | MAPTNPC1ALDH1A1RAB9AHPGD | |
| SCHEMBL17080310 | 0.76 | ALDH1A1 (0.66) | MAPTNPC1ALDH1A1RAB9AHPGD | |
| SCHEMBL9277361 | 0.76 | ALDH1A1 (0.70) | MAPTNPC1ALDH1A1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005675-A2 | RADIOLABELED O-METHYL PHOSPHOTRIESTER AND O-METHYL PHOSPHOROTHIOATE INTERNUCLEOSIDE LINKAGES AND OLIGONUCLEOTIDES CONTAINING THE SAME | HYBRIDON, INC. (US) | 1998-02-12 | — | — | WO | disclosed |