SCHEMBL69980

SCHEMBL69980

Oc1cc(Br)c(O)c(Br)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.65
TSHR P16473 2/20 0.65
TDP1 Q9NUW8 2/20 0.65
ALOX5 P09917 1/20 0.56
PTGS2 P35354 1/20 0.56
TTR P02766 2/20 0.50
ALOX15 P16050 2/20 0.50
ALOX12 P18054 2/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
ALDH1A1 P00352 2/20 0.50
ALB P02768 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA4 P22748 1/20 0.50
CA6 P23280 1/20 0.50
HPGD P15428 1/20 0.50
CASP1 P29466 1/20 0.50
RECQL P46063 1/20 0.50
HIF1A Q16665 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL9716111 0.97 CYP3A4 (0.61) CYP3A4TSHRTDP1ALOX5PTGS2
Propane SCHEMBL6575912 0.88 ALOX5 (0.54) CYP3A4TSHRTDP1ALOX5PTGS2
SCHEMBL12804864 0.84 ALOX5 (0.50) CYP3A4TSHRTDP1ALOX5PTGS2
SCHEMBL17659001 0.80 ALOX5 (0.52) CYP3A4TSHRTDP1ALOX5PTGS2
SCHEMBL13479148 0.80 ALOX5 (0.46) CYP3A4TSHRTDP1ALOX5PTGS2
SCHEMBL6544882 0.79 BACE1 (0.47) CYP3A4TSHRTDP1ALOX5PTGS2
SCHEMBL592990 0.79 APEX1 (0.53) CYP3A4TSHRTDP1ALOX5PTGS2
SCHEMBL18224 0.79 CYP3A4 (1.00) CYP3A4TSHRTDP1TTRALOX15
SCHEMBL581997 0.79 CRHBP (0.70) CYP3A4TSHRTDP1ALOX5PTGS2
SCHEMBL10546483 0.76 CYP3A4 (0.93) CYP3A4TSHRTDP1TTRALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6083671-A EQUIDENSITY IMAGES ON A BLACK-AND-WHITE, SILVER HALIDE FILM, HALOGEN-SUBSTITUTED HYDROQUINONE AS A DEVELOPING AGENT, SULFITE AS AN ANTIOXIDANT AND PRESERVATIVE, BORATE AS A BUFFER, THIOUREA AS A ?CHEMICAL SOLARIZER?. YUROW HARVEY WARREN (US) 2000-07-04 US claimed
CN-114213331-B URAT1 inhibitor and application thereof 江苏新元素医药科技有限公司 2024-06-21 CN disclosed
CN-117586272-A Heterocyclic compound, preparation method and application thereof in medicine 苏州信诺维医药科技股份有限公司 2024-02-23 CN disclosed
CN-117586213-A Preparation method of benzbromarone impurity B 常州寅盛药业有限公司 2024-02-23 CN disclosed
US-20240027902-A1 CHEMICALLY AMPLIFIED RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-01-25 US disclosed
US-20240027902-A1 CHEMICALLY AMPLIFIED RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-01-25 US disclosed
US-11835860-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-12-05 US disclosed
US-11835860-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-12-05 US disclosed
CN-111615515-B Heterocyclic compound, preparation method and application thereof in medicine 苏州信诺维医药科技股份有限公司 2023-11-24 CN disclosed
CN-110408024-B Polyimide precursor composition, polyamic acid, polyimide resin, polyimide film, and optical device 东京应化工业株式会社 2023-11-17 CN disclosed
WO-1994008269-A1 NLO SIDE CHAIN POLYMERS HAVING LOW OPTICAL LOSS AKZO NOBEL N.V. (NL) 1994-04-14 WO disclosed
EP-0212944-B1 MELT-PROCESSABLE AROMATIC COPOLYESTER Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1992-04-08 EP disclosed
US-5095088-A Cyclic polycarbonate oligomer containing spiro diLactam moieties SHELL OIL COMPANY (US) 1992-03-10 US disclosed
US-4910285-A Polyarylate polymers SHELL OIL COMPANY (US) 1990-03-20 US disclosed
US-4746721-A ENGINEERING PLASTICS KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1988-05-24 US disclosed
EP-0212944-A2 Melt-processable aromatic copolyester Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1987-03-04 EP disclosed
US-4612362-A Thermotropic polyester-carbonates containing 2,2-dimethyl-1,3-propanediol ALLIED CORPORATION (US) 1986-09-16 US disclosed
US-4398018-A Temperature stable thermotropic poly(ester carbonate) derived from t-butylhydroquinone ALLIED CORPORATION (US) 1983-08-09 US disclosed
US-4156663-A 260/857 R KANEBO, LTD. (JP) 1979-05-29 US disclosed
US-4072658-A FLAME RETARDANTS KANEBO, LTD. (JA) 1978-02-07 US disclosed