Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 17/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5544242 | 0.86 | PTGDR2 (0.76) | PTGDR2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8292005 | 0.85 | PTGDR2 (0.74) | PTGDR2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL11863429 | 0.85 | PTGDR2 (0.74) | PTGDR2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL19626502 | 0.85 | PTGDR2 (0.73) | PTGDR2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8291391 | 0.83 | MEN1 (0.76) | PTGDR2MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL11269805 | 0.82 | PTGDR2 (0.70) | PTGDR2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL10359068 | 0.82 | CYP1A2 (0.76) | PTGDR2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5815533 | 0.82 | PTGDR2 (0.69) | PTGDR2ALDH1A1MAPTGAA | |
| Fentiazac SCHEMBL16196751 | 0.80 | PTGDR2 (1.00) | PTGDR2MEN1KMT2AKDM4EALDH1A1 | |
| Fentiazac SCHEMBL24355 | 0.80 | PTGDR2 (1.00) | PTGDR2MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006085815-A1 | THIAZOLE DERIVATIVES, THEIR PROCESS FOR THEIR PREPARATION AND THEIR USE IN THERAPY | ASTRAZENECA AB (SE) | 2006-08-17 | — | — | WO | disclosed |
| WO-2006085815-A1 | THIAZOLE DERIVATIVES, THEIR PROCESS FOR THEIR PREPARATION AND THEIR USE IN THERAPY | ASTRAZENECA AB (SE) | 2006-08-17 | — | — | WO | disclosed |