Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | CDC7 | O00311 | 4/20 | 0.50 |
| ▸ | DBF4 | Q9UBU7 | 4/20 | 0.50 |
| ▸ | DHODH | Q02127 | 6/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | RARA | P10276 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11286051 | 0.87 | ALDH1A1 (0.70) | ALDH1A1HPGDHSD17B10CDC7DBF4 | |
| SCHEMBL5819987 | 0.85 | CDC7 (0.47) | ALDH1A1HPGDHSD17B10CDC7DBF4 | |
| SCHEMBL6183101 | 0.84 | CDC7 (0.52) | ALDH1A1HPGDHSD17B10CDC7DBF4 | |
| SCHEMBL5820220 | 0.83 | CDC7 (0.54) | ALDH1A1HPGDHSD17B10CDC7DBF4 | |
| SCHEMBL5820225 | 0.79 | CDC7 (0.52) | ALDH1A1HPGDHSD17B10CDC7DBF4 | |
| SCHEMBL27654539 | 0.77 | CDC7 (0.54) | ALDH1A1HPGDHSD17B10CDC7DBF4 | |
| SCHEMBL5136133 | 0.75 | SMN1; SMN2 (0.50) | ALDH1A1HPGDDHODHMEN1KMT2A | |
| SCHEMBL10268752 | 0.75 | CDC7 (0.51) | ALDH1A1HPGDHSD17B10CDC7DBF4 | |
| SCHEMBL275863 | 0.74 | NTRK1 (0.59) | ALDH1A1HPGDHSD17B10CDC7DBF4 | |
| SCHEMBL9644950 | 0.74 | ALDH1A1 (0.50) | ALDH1A1HPGDHSD17B10CDC7DBF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006085815-A1 | THIAZOLE DERIVATIVES, THEIR PROCESS FOR THEIR PREPARATION AND THEIR USE IN THERAPY | ASTRAZENECA AB (SE) | 2006-08-17 | — | — | WO | disclosed |