Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3834103 | 0.91 | RET (0.38) | KDM4EMEN1HPGDKMT2AHSD17B10 | |
| SCHEMBL3834104 | 0.91 | RET (0.38) | KDM4EMEN1HPGDKMT2AHSD17B10 | |
| SCHEMBL3830189 | 0.90 | MAPT (0.37) | KDM4EMEN1HPGDKMT2AHSD17B10 | |
| SCHEMBL3830191 | 0.90 | MAPT (0.37) | KDM4EMEN1HPGDKMT2AHSD17B10 | |
| SCHEMBL3833160 | 0.89 | RET (0.38) | KDM4ERET | |
| SCHEMBL4395555 | 0.88 | RAB9A (0.40) | KDM4EMEN1HPGDKMT2AHCAR2 | |
| SCHEMBL4395549 | 0.88 | RAB9A (0.40) | KDM4EMEN1HPGDKMT2AHCAR2 | |
| SCHEMBL3829267 | 0.87 | MEN1 (0.36) | KDM4EMEN1HPGDKMT2AHSD17B10 | |
| SCHEMBL3829264 | 0.87 | MEN1 (0.36) | KDM4EMEN1HPGDKMT2AHSD17B10 | |
| SCHEMBL3828151 | 0.86 | CNR1 (0.35) | RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006124897-A2 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITION | LEXICON GENETICS INCORPORATED (US) | 2006-11-23 | — | — | WO | disclosed |