Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAT2A | P31153 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5089792 | 0.79 | KMT2A (0.37) | MAPTTP53ALDH1A1 | |
| SCHEMBL5101221 | 0.79 | TACR1 (0.36) | MAPTTP53 | |
| SCHEMBL5094795 | 0.71 | CTSG (0.35) | MAPTALDH1A1 | |
| SCHEMBL6194690 | 0.70 | TACR1 (0.36) | MAPTALDH1A1 | |
| SCHEMBL5093112 | 0.70 | MAT2A (0.40) | ALDH1A1MAT2A | |
| SCHEMBL5089912 | 0.64 | NTRK1 (0.38) | MAPTMAT2A | |
| SCHEMBL6193839 | 0.64 | MTNR1A (0.46) | MAPT | |
| SCHEMBL3254021 | 0.62 | MTNR1A (0.53) | MAPTALDH1A1 | |
| SCHEMBL6211450 | 0.62 | TACR1 (0.36) | MAPTALDH1A1 | |
| SCHEMBL5101584 | 0.62 | NTRK1 (0.40) | MAT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1517909-B1 | NOVEL TETRACYCLIC ARYLCARBONYL INDOLES HAVING SEROTONIN RECEPTOR AFFINITY USEFUL AS THERAPEUTIC AGENTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SUVEN LIFE SCIENCES LTD (IN) | 2006-10-25 | — | — | EP | disclosed |