Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.31 |
| ▸ | FEN1 | P39748 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5820460 | 0.88 | MAPT (0.33) | MAPT | |
| SCHEMBL4764428 | 0.84 | AGTR1 (0.44) | MAPT | |
| SCHEMBL4774042 | 0.79 | ALOX5AP (0.36) | MAPTALOX5APFEN1 | |
| SCHEMBL4764436 | 0.73 | AGTR1 (0.45) | MAPT | |
| SCHEMBL4774377 | 0.73 | MAPT (0.34) | MAPT | |
| SCHEMBL4774359 | 0.72 | EDNRA (0.34) | MAPTALOX5APFEN1 | |
| SCHEMBL4764691 | 0.71 | RORC (0.34) | ALOX5APFEN1 | |
| SCHEMBL5525502 | 0.69 | ALDH1A1 (0.33) | ALOX5APFEN1 | |
| SCHEMBL4764007 | 0.68 | ALOX5AP (0.31) | ALOX5APFEN1 | |
| SCHEMBL6540183 | 0.67 | MAPT (0.35) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1237888-B1 | BIPHENYL SULFONAMIDES AS DUAL ANGIOTENSIN ENDOTHELIN RECEPTOR ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2006-09-13 | — | — | EP | disclosed |