Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.76 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.76 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.76 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.76 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.76 |
| ▸ | HPGD | P15428 | 2/20 | 0.76 |
| ▸ | CASP1 | P29466 | 1/20 | 0.76 |
| ▸ | RECQL | P46063 | 1/20 | 0.76 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.58 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.58 |
| ▸ | RET | P07949 | 1/20 | 0.58 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.58 |
| ▸ | PIM1 | P11309 | 1/20 | 0.58 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.58 |
| ▸ | KDR | P35968 | 1/20 | 0.58 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.58 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8623383 | 0.88 | CYP3A4 (0.76) | TSHRCYP3A4ALOX15HIF1AHSD17B10 | |
| SCHEMBL18647 | 0.87 | TSHR (1.00) | TSHRCYP3A4ALOX15HIF1AHSD17B10 | |
| SCHEMBL5173922 | 0.87 | TSHR (1.00) | TSHRCYP3A4ALOX15HIF1AHSD17B10 | |
| SCHEMBL11567514 | 0.85 | ALOX15 (0.86) | TSHRCYP3A4ALOX15HIF1AHSD17B10 | |
| Hydroquinone SCHEMBL28245323 | 0.83 | CYP3A4 (0.83) | TSHRCYP3A4ALOX15HIF1AHSD17B10 | |
| SCHEMBL4474163 | 0.82 | ALOX15 (0.73) | TSHRCYP3A4ALOX15HIF1AHSD17B10 | |
| SCHEMBL29466259 | 0.82 | ALOX15 (1.00) | TSHRCYP3A4ALOX15HIF1AHSD17B10 | |
| SCHEMBL6572582 | 0.82 | ALOX15 (1.00) | TSHRCYP3A4ALOX15HIF1AHSD17B10 | |
| Phenol SCHEMBL9189781 | 0.82 | CYP3A4 (0.73) | TSHRCYP3A4ALOX15HIF1AHSD17B10 | |
| SCHEMBL9773446 | 0.80 | CYP3A4 (0.76) | TSHRCYP3A4ALOX15HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6576739-B2 | Conversion of the hindered bisphenol to the corresponding bischloroformate and subsequent treatment with an amine catalyst and an aqueous base to effect polymerization by hydrolysis and condenstation of bischloroformate groups | GENERAL ELECTRIC COMPANY | 2003-06-10 | — | — | US | claimed |
| US-20020111456-A1 | Method of polycarbonate preparation | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2002-08-15 | — | — | US | claimed |
| WO-2001085825-A2 | METHOD OF POLYCARBONATE PREPARATION | GENERAL ELECTRIC COMPANY (US) | 2001-11-15 | — | — | WO | claimed |
| EP-1307499-B2 | CONTINUOUS PREPARATION OF POLYCARBONATE | GEN ELECTRIC (US) | 2012-02-15 | — | — | EP | disclosed |
| EP-1307499-B1 | CONTINUOUS PREPARATION OF POLYCARBONATE | GEN ELECTRIC (US) | 2006-10-25 | — | — | EP | disclosed |
| US-6576739-B2 | Conversion of the hindered bisphenol to the corresponding bischloroformate and subsequent treatment with an amine catalyst and an aqueous base to effect polymerization by hydrolysis and condenstation of bischloroformate groups | GENERAL ELECTRIC COMPANY | 2003-06-10 | — | — | US | disclosed |
| US-6562937-B2 | Endcapping with phenol | GENERAL ELECTRIC COMPANY | 2003-05-13 | — | — | US | disclosed |
| US-20020111456-A1 | Method of polycarbonate preparation | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2002-08-15 | — | — | US | disclosed |
| US-20020035234-A1 | Continuous preparation of polycarbonate | GENERAL ELECTRIC COMPANY | 2002-03-21 | — | — | US | disclosed |