Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.67 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.67 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CCKBR | P32239 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27428615 | 0.88 | ITGB3 (0.53) | ITGB3ITGA2BCA1CA2CA12 | |
| SCHEMBL6099449 | 0.88 | ITGB3 (0.75) | ITGB3ITGA2BCA1CA2CYP51A1 | |
| SCHEMBL4425018 | 0.88 | ITGB3 (0.75) | ITGB3ITGA2BCA1CA2CYP51A1 | |
| SCHEMBL27402980 | 0.87 | ITGB3 (0.52) | ITGB3ITGA2BCA1CA2CA12 | |
| SCHEMBL8650015 | 0.84 | ITGB3 (0.73) | ITGB3ITGA2BCA1CA2 | |
| SCHEMBL8020868 | 0.81 | ITGB3 (0.75) | ITGB3ITGA2BLNPEPCYP51A1 | |
| SCHEMBL13933091 | 0.81 | ITGB3 (0.83) | ITGB3ITGA2BCA1CA12CA9 | |
| Lamifiban SCHEMBL871446 | 0.81 | ITGB3 (1.00) | ITGB3ITGA2BCA1CA2CYP51A1 | |
| Lamifiban SCHEMBL4683 | 0.81 | ITGB3 (1.00) | ITGB3ITGA2BCA1CA2CYP51A1 | |
| SCHEMBL8689958 | 0.80 | ITGB3 (0.73) | ITGB3ITGA2BLNPEPCYP51A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006102674-A2 | DIPHENYLHETEROCYCLE CHOLESTEROL ABSORPTION INHIBITORS | MICROBIA, INC. (US) | 2006-09-28 | — | — | WO | disclosed |