Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 13/20 | 0.75 |
| ▸ | ITGA2B | P08514 | 13/20 | 0.75 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.45 |
| ▸ | PLG | P00747 | 2/20 | 0.45 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.45 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.45 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.45 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8689958 | 0.93 | ITGB3 (0.73) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7301514 | 0.91 | ITGB3 (0.62) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL27386352 | 0.90 | ITGB3 (0.61) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL27386345 | 0.90 | ITGB3 (0.61) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL8690540 | 0.89 | ITGB3 (0.70) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL13933091 | 0.89 | ITGB3 (0.83) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL8642742 | 0.88 | ITGB3 (0.69) | ITGB3ITGA2B | |
| SCHEMBL6099449 | 0.87 | ITGB3 (0.75) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL4425018 | 0.87 | ITGB3 (0.75) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| Lamifiban SCHEMBL4683 | 0.86 | ITGB3 (1.00) | ITGB3ITGA2BPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000029019-A1 | RESTORATION OF PLATELET AGGREGATION BY ANTIBODY ADMINISTRATION AFTER GPIIB/IIIA ANTAGONIST TREATMENT | G.D. SEARLE & CO. (US) | 2000-05-25 | — | — | WO | disclosed |
| EP-0912901-A1 | METHOD AND REAGENT FOR MONITORING BLOOD LEVELS OF ANTIPLATELET COMPOUNDS | G.D. SEARLE & CO. (US) | 1999-05-06 | — | — | EP | disclosed |
| WO-1997043650-A1 | METHOD AND REAGENT FOR MONITORING BLOOD LEVELS OF ANTIPLATELET COMPOUNDS | G.D. SEARLE & CO. (US) | 1997-11-20 | — | — | WO | disclosed |