Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 4/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | BPTF | Q12830 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | MERTK | Q12866 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4794040 | 0.78 | NPSR1 (0.41) | FTOEGLN1HIF1ANKDM5BUSP2 | |
| SCHEMBL3833975 | 0.71 | RET (0.37) | FTOEGLN1HIF1ANKDM5BDHFR | |
| SCHEMBL27735791 | 0.70 | AKR1C3 (0.35) | FTOEGLN1HIF1ANKDM5BDHFR | |
| SCHEMBL5820285 | 0.68 | ALDH1A1 (0.36) | FTOEGLN1HIF1ANKDM5BCYP1A2 | |
| SCHEMBL4792976 | 0.66 | KMT2A (0.47) | MAPK1MAPT | |
| SCHEMBL4794383 | 0.66 | CCNE1 (0.41) | CDK2MAPT | |
| SCHEMBL4793989 | 0.65 | FPR1 (0.36) | CYP1A2CYP3A4GRM5MAPK1MAPT | |
| SCHEMBL4794506 | 0.65 | CCNE1 (0.40) | CYP1A2CYP3A4CDK2 | |
| SCHEMBL5822296 | 0.64 | CCNE1 (0.42) | CYP1A2CYP3A4CDK2 | |
| SCHEMBL27735794 | 0.63 | MAPK1 (0.40) | DHFRBPTFGRM5MAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006124897-A2 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITION | LEXICON GENETICS INCORPORATED (US) | 2006-11-23 | — | — | WO | disclosed |