Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 8/20 | 0.42 |
| ▸ | CDK2 | P24941 | 8/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4394567 | 0.87 | RAB9A (0.42) | CCNE1CDK2ELANEKAT2BLMNA | |
| SCHEMBL5818277 | 0.83 | KDM4E (0.38) | CCNE1CDK2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4793477 | 0.82 | HTR3A (0.42) | CCNE1CDK2ELANETYK2PDE4D | |
| SCHEMBL4794383 | 0.81 | CCNE1 (0.41) | CCNE1CDK2ELANETYK2PDE4D | |
| SCHEMBL5820285 | 0.81 | ALDH1A1 (0.36) | MEN1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4793989 | 0.81 | FPR1 (0.36) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4792082 | 0.81 | CCNE1 (0.40) | CCNE1CDK2ELANETYK2PDE4D | |
| SCHEMBL4794506 | 0.80 | CCNE1 (0.40) | CCNE1CDK2ELANETYK2PDE4D | |
| SCHEMBL3827682 | 0.80 | CCNE1 (0.42) | CCNE1CDK2TYK2PDE4DPDE4B | |
| SCHEMBL4397397 | 0.79 | ELANE (0.43) | ELANEKAT2BLMNAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006124897-A2 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITION | LEXICON GENETICS INCORPORATED (US) | 2006-11-23 | — | — | WO | disclosed |