Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 12/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5819681 | 0.92 | CA9 (0.43) | KMT2AGAACA12CA1CA2 | |
| SCHEMBL5822322 | 0.92 | CA9 (0.43) | KMT2AGAACA12CA1CA2 | |
| SCHEMBL5815528 | 0.91 | GAA (0.38) | KMT2AGAACA12CA1CA2 | |
| SCHEMBL5817765 | 0.90 | CA1 (0.44) | CA12CA1CA2CA9PTGS2 | |
| SCHEMBL5821439 | 0.90 | CA9 (0.44) | KMT2AGAACA12CA1CA2 | |
| SCHEMBL5815486 | 0.89 | PTGS2 (0.39) | KMT2AGAACA12CA1CA2 | |
| SCHEMBL5821281 | 0.88 | PTGS2 (0.38) | KMT2AGAACA12CA1CA2 | |
| SCHEMBL5821767 | 0.81 | ESR1 (0.36) | GAAPTGS2PTGS1 | |
| SCHEMBL5820891 | 0.79 | ALDH1A1 (0.41) | GAAPTGS2PTGS1 | |
| SCHEMBL5821417 | 0.77 | ALDH1A1 (0.36) | KMT2AMEN1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006129181-A2 | PREPARATION OF 4-PYRIMIDONE DERIVATIVES FOR TREATING INFLAMMATORY DISEASES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2006-12-07 | — | — | WO | claimed |
| WO-2006129181-A2 | PREPARATION OF 4-PYRIMIDONE DERIVATIVES FOR TREATING INFLAMMATORY DISEASES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2006-12-07 | — | — | WO | disclosed |