Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.47 |
| ▸ | DRD3 | P35462 | 4/20 | 0.47 |
| ▸ | HTR2A | P28223 | 5/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 6/20 | 0.41 |
| ▸ | HTR7 | P34969 | 3/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5815836 | 0.91 | DRD2 (0.52) | DRD2DRD3HTR2AMCHR1HTR1A | |
| SCHEMBL5807070 | 0.91 | DRD2 (0.53) | DRD2DRD3HTR2AMCHR1HTR1A | |
| Hydrochloric Acid SCHEMBL5807960 | 0.90 | DRD2 (0.53) | DRD2DRD3HTR2AMCHR1HTR1A | |
| SCHEMBL5807093 | 0.82 | DRD2 (0.61) | DRD2DRD3HTR2AMCHR1HTR1A | |
| Hydrochloric Acid SCHEMBL5807967 | 0.81 | DRD2 (0.60) | DRD2DRD3HTR2AMCHR1HTR1A | |
| SCHEMBL5820005 | 0.81 | DRD2 (0.62) | DRD2DRD3HTR2AMCHR1HTR1A | |
| SCHEMBL5805493 | 0.78 | ADRA1A (0.53) | DRD2HTR2AMCHR1ADRA1A | |
| Hydrochloric Acid SCHEMBL5821924 | 0.78 | DRD2 (0.49) | DRD2DRD3HTR2AMCHR1HTR1A | |
| Hydrochloric Acid SCHEMBL5805262 | 0.78 | ADRA1A (0.52) | ADRA1A | |
| SCHEMBL5816138 | 0.77 | DRD2 (0.52) | DRD2DRD3HTR2AHTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006117760-A1 | ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |