Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | CCR6 | P51684 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.47 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | RGS4 | P49798 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL151352 | 0.74 | MAPT (0.50) | ALDH1A1MAPTNPSR1GAACCR6 | |
| SCHEMBL27277165 | 0.73 | MAPT (0.53) | ALDH1A1MAPTNPSR1GAACCR6 | |
| SCHEMBL152254 | 0.71 | MAPT (0.55) | ALDH1A1MAPTNPSR1GAACCR6 | |
| SCHEMBL9418708 | 0.70 | ALDH1A1 (0.50) | ALDH1A1MAPTNPSR1GAACCR6 | |
| SCHEMBL149927 | 0.69 | MAPT (0.53) | ALDH1A1MAPTNPSR1GAACCR6 | |
| SCHEMBL27519378 | 0.69 | MAPT (0.53) | ALDH1A1MAPTNPSR1GAACCR6 | |
| SCHEMBL152799 | 0.69 | MAPT (0.53) | ALDH1A1MAPTNPSR1GAACCR6 | |
| SCHEMBL28770986 | 0.69 | MAPT (0.53) | ALDH1A1MAPTNPSR1GAACCR6 | |
| SCHEMBL152219 | 0.69 | MAPT (0.53) | ALDH1A1MAPTNPSR1GAACCR6 | |
| SCHEMBL303331 | 0.68 | ALDH1A1 (0.51) | ALDH1A1MAPTNPSR1GAACCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005028678-A9 | METHODS AND MATERIALS FOR IDENTIFYING AGENTS WHICH MODULATE BONE REMODELING AND AGENTS IDENTIFIED THEREBY | WYETH CORP (US) | 2006-08-31 | — | — | WO | disclosed |