SCHEMBL149927

SCHEMBL149927

CN1C(=O)C=C(c2ccccc2)C1=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.53
ALDH1A1 P00352 3/20 0.53
NPSR1 Q6W5P4 3/20 0.53
GAA P10253 2/20 0.53
CCR6 P51684 2/20 0.53
HPGD P15428 2/20 0.53
ALOX12 P18054 2/20 0.53
CACNA1B Q00975 2/20 0.53
APBA1 Q02410 2/20 0.53
LMNA P02545 2/20 0.50
HTT P42858 1/20 0.50
RGS4 P49798 1/20 0.46
MAOA P21397 1/20 0.45
MAOB P27338 1/20 0.45
BACE1 P56817 4/20 0.43
HCRTR1 O43613 1/20 0.42
S1PR4 O95977 1/20 0.42
HSP90AA1 P07900 1/20 0.42
S1PR1 P21453 1/20 0.42
HSD17B3 P37058 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethane SCHEMBL8564354 0.98 MAPT (0.51) MAPTALDH1A1NPSR1GAACCR6
SCHEMBL10996746 0.82 MAPT (0.41) MAPTALDH1A1NPSR1GAACCR6
SCHEMBL10994041 0.82 RGS4 (0.53) MAPTALDH1A1NPSR1GAACCR6
SCHEMBL7039010 0.81 MAPT (0.53) MAPTALDH1A1HPGDCACNA1BAPBA1
SCHEMBL23565762 0.80 MAOA (0.42) MAPTALDH1A1NPSR1GAACCR6
SCHEMBL28901342 0.80 MAOA (0.42) MAPTALDH1A1NPSR1GAACCR6
SCHEMBL4974025 0.80 MAOA (0.42) MAPTALDH1A1NPSR1GAACCR6
SCHEMBL6003729 0.80 SIGMAR1 (0.38) MAPTALDH1A1NPSR1GAACCR6
SCHEMBL8569835 0.79 MAPT (0.49) MAPTALDH1A1NPSR1GAACCR6
SCHEMBL6003662 0.78 PGR (0.46) MAPTALDH1A1GAAHPGDHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 724 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025079950-A1 METHOD FOR MANUFACTURING MALEIMIDE-BASED QUATERNARY COPOLYMER AND MALEIMIDE-BASED QUATERNARY COPOLYMER MANUFACTURING THEREFROM 금호석유화학 주식회사 2025-04-17 WO claimed
CN-110418783-B Process for purifying N-substituted maleimides 株式会社LG化学 2022-10-04 CN claimed
CN-110198927-B Process for purifying N-substituted maleimides 株式会社LG化学 2022-08-12 CN claimed
EP-3636634-B1 METHOD FOR PURIFYING N-SUBSTITUTED MALEIMIDE LG CHEMICAL LTD (KR) 2022-06-22 EP claimed
US-11345661-B2 Method for purifying N-substituted maleimide LG CHEM, LTD. (KR) 2022-05-31 US claimed
CN-114539266-A Maleimidocarbazole compound and synthesis method thereof 湘潭大学 2022-05-27 CN claimed
CN-109071432-B Synthesis method of N-substituted maleimide by using solid acid catalyst 株式会社LG化学 2022-04-12 CN claimed
US-20210355083-A1 METHOD FOR PURIFYING N-SUBSTITUTED MALEIMIDE LG CHEM, LTD. (KR) 2021-11-18 US claimed
US-10899708-B2 Method for purifying n-substituted maleimide LG CHEM, LTD. (KR) 2021-01-26 US claimed
EP-3578544-B1 METHOD FOR PURIFYING N-SUBSTITUTED MALEIMIDE LG CHEMICAL LTD (KR) 2020-12-30 EP claimed
US-20110297896-A1 ACRYLIC RESIN COMPOSITION, AND OPTICAL FILM COMPRISING SAME LG CHEM, LTD. (KR) 2011-12-08 US claimed
US-20100240851-A1 MALEIMIDE-ALPHA-ALKYLSTYRENE-BASED TERPOLYMER WITH LOW MOLTEN VISCOSITY AND CONTINUOUS BULK PROCESS FOR PRODUCING IT KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2010-09-23 US claimed
US-20100036065-A1 Maleimide-alpha-alkylstyrene-based tetrapolymer with low molten viscosity and continuous bulk process for producing it KOREA KUMBO PETROCHEMICAL CO., LTD. (KR) 2010-02-11 US claimed
US-5164425-A Allyl terminated polyesters, fillers SHOWA DENKO K.K. (JP) 1992-11-17 US claimed
EP-0493631-A1 Artificial marble composition SHOWA DENKO KABUSHIKI KAISHA (JP) 1992-07-08 EP claimed
EP-0230597-B1 METHOD FOR INHIBITING POLYMERIZATION OF MALEIMIDES Nippon Shokubai Kagaku Kogyo Co., Ltd (JP) 1992-04-08 EP claimed
EP-0230597-A2 Method for inhibiting polymerization of maleimides Nippon Shokubai Kagaku Kogyo Co., Ltd (JP) 1987-08-05 EP claimed
US-4342860-A AN UNSATUREATED IMIDE IS USED WITH A DI OR POLYISOCYANATE TO FORM A POLYIMIDE POLYMER RHONE-POULENC INDUSTRIES (FR) 1982-08-03 US claimed
US-4342861-A AN UNSATURATGED IMIDE AND A DI OR POLYISOCYANATE GO TO MAKE UP A POLYIMIDE POLYMER WHICH ALSO CONTAINS REPEATING AMIDE GROUPS RHONE-POULENC INDUSTRIES (FR) 1982-08-03 US claimed
US-4302572-A MOLDING MATERIALS; COATINGS; HEAT RESISTANCE; THIN FILMS RHONE-POULENC INDUSTRIES (FR) 1981-11-24 US claimed