Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.58 |
| ▸ | CNR1 | P21554 | 1/20 | 0.58 |
| ▸ | PPARG | P37231 | 2/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | PTGES | O14684 | 1/20 | 0.51 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.51 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1076364 | 0.88 | PTGS2 (0.65) | CNR2PPARGPTGS2PTGS1AKR1C3 | |
| SCHEMBL8579955 | 0.88 | LMNA (0.65) | PPARGPTGS2PTGS1AKR1C3AKR1C2 | |
| SCHEMBL11436509 | 0.87 | PTGS2 (0.64) | CNR2PPARGPTGS2PTGS1AKR1C3 | |
| SCHEMBL6025282 | 0.87 | PTGS1 (0.47) | CNR2CNR1PPARGPTGS2PTGS1 | |
| SCHEMBL5799148 | 0.86 | PTGS2 (0.52) | CNR2PPARGPTGS2PTGS1AKR1C3 | |
| Water SCHEMBL11448360 | 0.86 | PTGS2 (0.62) | CNR2PPARGPTGS2PTGS1AKR1C3 | |
| Water SCHEMBL11448358 | 0.86 | PTGS2 (0.62) | CNR2PPARGPTGS2PTGS1AKR1C3 | |
| SCHEMBL3252299 | 0.85 | CNR2 (0.56) | CNR2CNR1PPARGPTGS2PTGS1 | |
| SCHEMBL5797468 | 0.84 | AKR1C3 (0.52) | CNR2PPARGPTGS2PTGS1AKR1C3 | |
| SCHEMBL3240338 | 0.83 | PTGS1 (0.48) | CNR2CNR1PPARGPTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1628532-A2 | METHODS FOR THE PROTECTION OF MEMORY AND COGNITION | Microbia, Inc. (US) | 2006-03-01 | — | — | EP | claimed |
| WO-2004108085-A2 | METHODS FOR THE PROTECTION OF MEMORY AND COGNITION | MICROBIA, INC. (US) | 2004-12-16 | — | — | WO | claimed |
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |
| EP-1628532-A2 | METHODS FOR THE PROTECTION OF MEMORY AND COGNITION | Microbia, Inc. (US) | 2006-03-01 | — | — | EP | disclosed |
| WO-2004108085-A2 | METHODS FOR THE PROTECTION OF MEMORY AND COGNITION | MICROBIA, INC. (US) | 2004-12-16 | — | — | WO | disclosed |