Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 3/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5553721 | 0.88 | AKR1C3 (0.44) | PTGS1PTGS2MAPTPKMKMT2A | |
| SCHEMBL5822002 | 0.87 | CNR2 (0.58) | PTGS1PTGS2CNR1CNR2MAPT | |
| SCHEMBL6025591 | 0.85 | PTGS2 (0.48) | PTGS1PTGS2CNR2MAPTKMT2A | |
| SCHEMBL5560588 | 0.84 | MAPT (0.39) | PTGS2CNR1CNR2MAPTPKM | |
| SCHEMBL5799040 | 0.83 | PTGS2 (0.46) | PTGS1PTGS2MAPTPKMKMT2A | |
| SCHEMBL5800412 | 0.83 | PTGS2 (0.46) | PTGS1PTGS2MAPTKMT2AABCB11 | |
| SCHEMBL6025157 | 0.82 | PTGS1 (0.45) | PTGS1PTGS2CNR1CNR2MAPT | |
| SCHEMBL6025108 | 0.81 | CNR2 (0.47) | PTGS1PTGS2CNR1CNR2MAPT | |
| SCHEMBL5558582 | 0.81 | PTGS2 (0.47) | PTGS1PTGS2LMNAHPGDHTT | |
| SCHEMBL5814619 | 0.80 | CNR1 (0.38) | PTGS2CNR1CNR2MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1628532-A2 | METHODS FOR THE PROTECTION OF MEMORY AND COGNITION | Microbia, Inc. (US) | 2006-03-01 | — | — | EP | claimed |
| WO-2004108085-A2 | METHODS FOR THE PROTECTION OF MEMORY AND COGNITION | MICROBIA, INC. (US) | 2004-12-16 | — | — | WO | claimed |
| EP-1628532-A2 | METHODS FOR THE PROTECTION OF MEMORY AND COGNITION | Microbia, Inc. (US) | 2006-03-01 | — | — | EP | disclosed |
| WO-2004108085-A2 | METHODS FOR THE PROTECTION OF MEMORY AND COGNITION | MICROBIA, INC. (US) | 2004-12-16 | — | — | WO | disclosed |