SCHEMBL5822019

SCHEMBL5822019

CC(=O)OC1=C(C)C(=O)c2c(OC(C)=O)cccc2C1=O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.58
ALDH1A1 P00352 4/20 0.58
KMT2A Q03164 3/20 0.58
MAPT P10636 3/20 0.58
LMNA P02545 3/20 0.58
TTR P02766 2/20 0.58
MAPK1 P28482 2/20 0.58
HPGD P15428 2/20 0.58
MEN1 O00255 2/20 0.58
HTT P42858 2/20 0.58
ABCC4 O15439 1/20 0.58
USP2 O75604 1/20 0.58
TP53 P04637 1/20 0.58
HSP90AA1 P07900 1/20 0.58
CHRM2 P08172 1/20 0.58
HSP90AB1 P08238 1/20 0.58
HTR1A P08908 1/20 0.58
ADRA2A P08913 1/20 0.58
ADORA3 P0DMS8 1/20 0.58
CHRM1 P11229 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5613348 0.86 ALDH1A1 (0.73) KDM4EALDH1A1KMT2AMAPTLMNA
SCHEMBL23938881 0.85 FGFR1 (0.43) KDM4EALDH1A1KMT2AMAPTLMNA
SCHEMBL11101186 0.83 TTR (0.72) KDM4EALDH1A1KMT2AMAPTLMNA
SCHEMBL5817030 0.83 PIM1 (0.49) KDM4EALDH1A1KMT2AMAPTLMNA
SCHEMBL23743764 0.83 KMT2A (0.64) KDM4EALDH1A1KMT2AMAPTLMNA
SCHEMBL1287084 0.81 KDM4E (0.58) KDM4EALDH1A1KMT2AMAPTLMNA
SCHEMBL11526641 0.79 PIM1 (0.69) KDM4EALDH1A1KMT2AMAPTLMNA
SCHEMBL9538649 0.79 MEN1 (0.64) KDM4EALDH1A1KMT2AMAPTLMNA
SCHEMBL686744 0.79 CDC25B (0.59) KDM4EALDH1A1KMT2AMAPTLMNA
SCHEMBL14003223 0.79 TTR (0.71) KDM4EALDH1A1KMT2AMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006107827-A1 SKIN BONDING PROCESS CREIGHTON UNIVERSITY (US) 2006-10-12 WO disclosed