Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 9/20 | 0.59 |
| ▸ | CDC25A | P30304 | 7/20 | 0.59 |
| ▸ | APEX1 | P27695 | 2/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.48 |
| ▸ | MAP2K7 | O14733 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11365625 | 0.90 | MAPT (0.54) | CDC25BCDC25AAPEX1MAP2K7KDM4E | |
| SCHEMBL18220965 | 0.86 | CDC25B (0.47) | CDC25BCDC25AAPEX1AURKAAURKB | |
| SCHEMBL10959287 | 0.81 | IDO1 (0.54) | CDC25BCDC25AAPEX1MAP2K7KDM4E | |
| SCHEMBL23938881 | 0.80 | FGFR1 (0.43) | CDC25BCDC25AKDM4EALDH1A1LMNA | |
| SCHEMBL26781790 | 0.80 | HSP90AA1 (0.49) | CDC25BCDC25AMAP2K7KDM4EALDH1A1 | |
| SCHEMBL5822019 | 0.79 | KDM4E (0.58) | APEX1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL14313792 | 0.78 | FGFR1 (0.50) | CDC25BCDC25AAPEX1MAP2K7KDM4E | |
| SCHEMBL22323640 | 0.76 | MAPT (0.44) | KDM4EALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL29941466 | 0.75 | CDC25B (0.68) | CDC25BCDC25AAURKAAURKBMAP2K7 | |
| SCHEMBL571026 | 0.75 | CDC25B (0.68) | CDC25BCDC25AAURKAAURKBMAP2K7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170138953-A1 | METHODS FOR DETECTING AND QUANTIFYING NON-POLAR ANALYTES WITH HIGH SENSITIVITY | WATERS TECHNOLOGIES CORPORATION | 2017-05-18 | — | — | US | disclosed |
| US-8299036-B2 | Active agent combinations with insecticidal and acaricidal properties | BAYER CROPSCIENCE AG (DE) | 2012-10-30 | — | — | US | disclosed |
| US-20120010076-A1 | ACTIVE AGENT COMBINATIONS WITH INSECTICIDAL AND ACARICIDAL PROPERITIES | BAYER CROPSCIENCE AG (DE) | 2012-01-12 | — | — | US | disclosed |
| US-8044085-B2 | Active agent combinations with insecticidal and acaricidal properties | BAYER CROPSCIENCE AG (DE) | 2011-10-25 | — | — | US | disclosed |
| US-20110124588-A1 | SYNERGISTIC ACTIVE INGREDIENT COMBINATIONS | BAYER CROPSCIENCE AG (DE) | 2011-05-26 | — | — | US | disclosed |
| US-20100311677-A1 | Active Ingredient Combinations Having Insecticidal and Acaricidal Properties | BAYER CROPSCIENCE AG (DE) | 2010-12-09 | — | — | US | disclosed |
| US-20100204167-A1 | ACTIVE COMPOUND COMBINATIONS HAVING INSECTICIDAL AND ACARICIDAL PROPERTIES | BAYER CROPSCIENCE AG (DE) | 2010-08-12 | — | — | US | disclosed |
| US-20100197737-A1 | ACTIVE AGENT COMBINATIONS HAVING INSECTICIDAL AND ACARICIDAL PROPERTIES | BAYER CROPSCIENCE AG (DE) | 2010-08-05 | — | — | US | disclosed |
| US-20100168042-A1 | ACTIVE AGENT COMBINATIONS WITH INSECTICIDAL AND ACARICIDAL PROPERTIES | BAYER CROPSCIENCE AG (DE) | 2010-07-01 | — | — | US | disclosed |
| US-20090286788-A1 | Active agent combinations with insecticidal and acaricidal properties | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2009-11-19 | — | — | US | disclosed |
| US-7585887-B2 | Active agent combinations with insecticidal and acaricidal properties | BAYER CROPSCIENCE AG (DE) | 2009-09-08 | — | — | US | disclosed |
| US-20080027114-A1 | Active Agent Combinations with Insecticidal and Acaricidal Properties | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2008-01-31 | — | — | US | disclosed |
| US-7205289-B2 | Combinations of active ingredients with insecticidal and acaricidal properties | BAYER AKTIENGESELLSCHAFT (DE) | 2007-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124588-A1 | SYNERGISTIC ACTIVE INGREDIENT COMBINATIONS | ACHE, ACAT2, ACAT1 | CDC25B 309/4885CDC25A 684/4885APEX1 4606/4885 |
| US-20100197737-A1 | ACTIVE AGENT COMBINATIONS HAVING INSECTICIDAL AND ACARICIDAL PROPERTIES | ACHE, AADAC, AMY1A | CDC25B 1618/4885CDC25A 1023/4885APEX1 4274/4885 |
| US-20080027114-A1 | Active Agent Combinations with Insecticidal and Acaricidal Properties | AADAC, ACAA2, AAAS | CDC25B 968/4885CDC25A 712/4885APEX1 3497/4885 |
| US-20120010076-A1 | ACTIVE AGENT COMBINATIONS WITH INSECTICIDAL AND ACARICIDAL PROPERITIES | ACAA2, ACHE, AADAC | CDC25B 733/4885CDC25A 728/4885APEX1 3957/4885 |
| US-20090286788-A1 | Active agent combinations with insecticidal and acaricidal properties | ACAA2, ACHE, AADAC | CDC25B 562/4885CDC25A 631/4885APEX1 3911/4885 |
| US-20100204167-A1 | ACTIVE COMPOUND COMBINATIONS HAVING INSECTICIDAL AND ACARICIDAL PROPERTIES | ACHE, ACAT2, ACAT1 | CDC25B 1369/4885CDC25A 1548/4885APEX1 3473/4885 |
| US-20100168042-A1 | ACTIVE AGENT COMBINATIONS WITH INSECTICIDAL AND ACARICIDAL PROPERTIES | AADAC, ACAA2, AAAS | CDC25B 968/4885CDC25A 712/4885APEX1 3497/4885 |
| US-20100311677-A1 | Active Ingredient Combinations Having Insecticidal and Acaricidal Properties | ACHE, ACAT2, ACAT1 | CDC25B 646/4885CDC25A 912/4885APEX1 4552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.