Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | TTR | P02766 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | USP2 | O75604 | 2/20 | 0.64 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.64 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.64 |
| ▸ | CASP7 | P55210 | 2/20 | 0.64 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.64 |
| ▸ | HTR1A | P08908 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5613348 | 0.92 | ALDH1A1 (0.73) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL11526641 | 0.91 | PIM1 (0.69) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL11101186 | 0.85 | TTR (0.72) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| Diacerein SCHEMBL5712120 | 0.85 | MEN1 (0.84) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL23743764 | 0.84 | KMT2A (0.64) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL5857040 | 0.83 | MEN1 (0.67) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL8382011 | 0.82 | MEN1 (0.84) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL17460659 | 0.82 | MAOA (0.56) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL14003223 | 0.81 | TTR (0.71) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL11000611 | 0.80 | KDM4E (0.59) | MEN1KMT2AALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993005054-A1 | OXAZAPHOSPHORINES USEFUL AS ANTITUMOR AGENTS, A PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1993-03-18 | — | — | WO | disclosed |