Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 15/20 | 0.43 |
| ▸ | CDK9 | P50750 | 15/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5818162 | 0.92 | TLR9 (0.45) | CCNT1CDK9CARM1TLR9TLR7 | |
| SCHEMBL5820172 | 0.88 | TLR9 (0.41) | CCNT1CDK9CARM1TLR9TLR7 | |
| SCHEMBL5817165 | 0.86 | TLR9 (0.56) | CCNT1CDK9CARM1TLR9TLR7 | |
| SCHEMBL5821305 | 0.83 | PDE4B (0.53) | CCNT1CDK9TLR7PDE4B | |
| SCHEMBL5824218 | 0.83 | HRH3 (0.43) | TLR9TLR7HRH3 | |
| SCHEMBL5824277 | 0.80 | TLR9 (0.66) | CARM1TLR9TLR7 | |
| SCHEMBL5821272 | 0.79 | HRH3 (0.40) | CARM1TLR9TLR7HRH3 | |
| SCHEMBL5821888 | 0.75 | DRD2 (0.56) | CCNT1CDK9CARM1TLR9TLR7 | |
| SCHEMBL5822415 | 0.74 | PDE4B (0.53) | TLR9TLR7PDE4B | |
| SCHEMBL5824183 | 0.74 | CCNT1 (0.39) | CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006113458-A1 | HETEROCYCLIC INHIBITORS OF PROTEIN ARGININE METHYL TRANSFERASES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-10-26 | — | — | WO | disclosed |
| US-20060235037-A1 | Heterocyclic inhibitors of protein arginine methyl transferases | BRISTOL-MYERS SQUIBB COMPANY | 2006-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060235037-A1 | Heterocyclic inhibitors of protein arginine methyl transferases | PRMT1, PRMT3, PRMT8 | CCNT1 263/4885CDK9 1060/4885CARM1 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.