Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1883587 | 0.77 | ACHE (0.36) | ALDH1A1ADRB2ADRB1ADRB3MEN1 | |
| SCHEMBL1885646 | 0.76 | ADRB2 (0.37) | ALDH1A1HRH4HRH3ADRB2ADRB1 | |
| SCHEMBL1884857 | 0.74 | ALDH1A1 (0.40) | ALDH1A1HRH4HRH3ADRB2ADRB1 | |
| SCHEMBL1884860 | 0.74 | ADRB2 (0.39) | ALDH1A1TSHRMDM2ADRB2ADRB1 | |
| SCHEMBL1889531 | 0.74 | ADRB2 (0.39) | ALDH1A1TSHRMDM2ADRB2ADRB1 | |
| SCHEMBL5822251 | 0.72 | ALDH1A1 (0.33) | ALDH1A1HRH3TSHRMDM2ADRB2 | |
| SCHEMBL205737 | 0.70 | ALDH1A1 (0.50) | ALDH1A1ADRB2ADRB1ADRB3MEN1 | |
| SCHEMBL8845363 | 0.70 | ALDH1A1 (0.50) | ALDH1A1ADRB2ADRB1ADRB3MEN1 | |
| SCHEMBL24139753 | 0.70 | ALDH1A1 (0.36) | ALDH1A1TSHRMDM2ADRB2ADRB1 | |
| SCHEMBL1892875 | 0.70 | ADRB2 (0.43) | ALDH1A1ADRB2ADRB1ADRB3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050471-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF SULFINIC ACIDS, METHODS OF SYNTHESIS, AND USE | XENOPORT, INC. (US) | 2006-05-11 | — | — | WO | disclosed |