Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL201803 | 0.92 | — | — | |
| SCHEMBL30702093 | 0.88 | TACR1 (0.37) | TACR1SLC6A4KCNH2CYP1A2CYP3A4 | |
| SCHEMBL380517 | 0.88 | TACR1 (0.37) | TACR1SLC6A4KCNH2CYP1A2CYP3A4 | |
| SCHEMBL5822863 | 0.84 | — | — | |
| SCHEMBL5198042 | 0.74 | POLB (0.38) | — | |
| SCHEMBL25273540 | 0.73 | CYP11B1 (0.36) | — | |
| SCHEMBL31052358 | 0.73 | CYP11B1 (0.36) | — | |
| SCHEMBL8407628 | 0.72 | LPL (0.37) | — | |
| SCHEMBL1241080 | 0.72 | ENPP2 (0.49) | — | |
| SCHEMBL6490220 | 0.72 | IDO1 (0.48) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006038923-A2 | ARYL SUBSTITUTED IMIDAZONAPHTHYRIDINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-04-13 | — | — | WO | disclosed |