SCHEMBL8407628

SCHEMBL8407628

CCc1cc(CO[Si](C)(C)C(C)(C)C)cc(B(O)O)c1

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LPL P06858 1/20 0.37
LIPG Q9Y5X9 1/20 0.37
BACE1 P56817 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12293557 0.81
SCHEMBL17615243 0.80 LOXL2 (0.30)
SCHEMBL201803 0.79
SCHEMBL1241080 0.79 ENPP2 (0.49) LPLLIPG
SCHEMBL17615244 0.78 BACE1 (0.32) BACE1
SCHEMBL9030829 0.78 LPL (0.46) LPLLIPGBACE1
SCHEMBL22198892 0.77 BACE1 (0.35) BACE1
SCHEMBL3791528 0.76 LPL (0.58) LPLLIPG
SCHEMBL11942311 0.74 IDO1 (0.38)
SCHEMBL25617253 0.74 CHRNB2 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8354515-B2 Oligonucleotide derivative, labeling agent and use for labeling agent JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2013-01-15 US disclosed
US-20120126175-A1 OLIGONUCLEOTIDE DERIVATIVE, LABELING AGENT AND USE FOR LABELING AGENT JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2012-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120126175-A1 OLIGONUCLEOTIDE DERIVATIVE, LABELING AGENT AND USE FOR LABELING AGENT UPF1, SPIN4, SRRT LPL 4314/4885LIPG 4251/4885BACE1 2216/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.