Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 13/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GLS | O94925 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3811826 | 0.90 | KMT2A (0.39) | KLKB1PDE2AGLS | |
| SCHEMBL5822386 | 0.86 | CNR2 (0.42) | CNR2KLKB1NAMPTCYP1A2CYP3A4 | |
| SCHEMBL27714954 | 0.86 | KMT2A (0.47) | — | |
| SCHEMBL3822101 | 0.82 | KMT2A (0.40) | KLKB1PDE2ANAMPTGLS | |
| SCHEMBL27735796 | 0.80 | PTK2 (0.41) | CAMK2D | |
| SCHEMBL27714952 | 0.78 | WEE1 (0.44) | CAMK2D | |
| SCHEMBL3816625 | 0.77 | TRPV1 (0.38) | NAMPTGLS | |
| SCHEMBL3820599 | 0.76 | KMT2A (0.39) | KLKB1CYP2C9GLS | |
| SCHEMBL5822504 | 0.75 | TRPV1 (0.45) | CNR2 | |
| SCHEMBL3812466 | 0.74 | DGAT2 (0.39) | GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101252935-A | Pyrrolopyridine, pyrrolopyrimidine and pyrazolopyridine compounds, compositions containing them, and methods of their use | LEXICON GENETICS INC (US) | 2008-08-27 | — | — | CN | disclosed |
| WO-2006124897-A2 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITION | LEXICON GENETICS INCORPORATED (US) | 2006-11-23 | — | — | WO | disclosed |