Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 11/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | GLS | O94925 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3820599 | 0.90 | KMT2A (0.39) | KLKB1PDE10AGLSELANECYP2C9 | |
| SCHEMBL5822872 | 0.86 | CNR2 (0.41) | CNR2KLKB1GLSNAMPTCYP1A2 | |
| SCHEMBL3821871 | 0.79 | GLS (0.39) | KLKB1PDE10AGLSELANECDK2 | |
| SCHEMBL3822101 | 0.76 | KMT2A (0.40) | CSF1RKLKB1GLSNAMPT | |
| SCHEMBL3811826 | 0.76 | KMT2A (0.39) | KLKB1GLS | |
| SCHEMBL27714954 | 0.72 | KMT2A (0.47) | PDE10A | |
| SCHEMBL3816625 | 0.71 | TRPV1 (0.38) | CSF1RGLSNAMPT | |
| SCHEMBL5822504 | 0.69 | TRPV1 (0.45) | CNR2PDE10A | |
| SCHEMBL3812466 | 0.69 | DGAT2 (0.39) | GLS | |
| SCHEMBL3813771 | 0.67 | KMT2A (0.44) | CNR2PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006124897-A2 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITION | LEXICON GENETICS INCORPORATED (US) | 2006-11-23 | — | — | WO | disclosed |