Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3569482 | 0.87 | RAB9A (0.42) | MAPTHTTTSHRKDM4EL3MBTL1 | |
| SCHEMBL5822982 | 0.83 | MAPT (0.45) | MAPTHPGDHTTTSHRCCR5 | |
| SCHEMBL3569479 | 0.79 | MAPT (0.43) | MAPTHPGDHTTTSHRKDM4E | |
| SCHEMBL3566849 | 0.79 | HTT (0.41) | MAPTHTTTSHRLMNAPOLB | |
| SCHEMBL3570709 | 0.79 | HTT (0.42) | MAPTHTTTSHRLMNATP53 | |
| SCHEMBL3573944 | 0.77 | HTT (0.40) | MAPTHTTTSHRTP53L3MBTL1 | |
| SCHEMBL3566847 | 0.71 | MAPT (0.35) | MAPTHTTTSHRKDM4ELMNA | |
| SCHEMBL3570706 | 0.71 | F10 (0.40) | MAPTHTTKDM4ELMNATP53 | |
| SCHEMBL3561245 | 0.70 | ROCK2 (0.41) | MAPTKDM4EALDH1A1 | |
| SCHEMBL3573941 | 0.69 | SMN1; SMN2 (0.34) | MAPTHTTTSHRKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006063113-A2 | UREAS AS FACTOR XA INHIBITORS | PORTOLA PHARMACEUTICALS, INC. (US) | 2006-06-15 | — | — | WO | disclosed |