Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | INSR | P06213 | 1/20 | 0.47 |
| ▸ | IGF1R | P08069 | 1/20 | 0.47 |
| ▸ | NEK2 | P51955 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 3/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.44 |
| ▸ | METAP2 | P50579 | 2/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5823141 | 0.88 | ROCK2 (0.47) | MAPTKDM4EMEN1KMT2ANEK2 | |
| SCHEMBL28922588 | 0.76 | LCK (0.35) | MAPTMEN1KMT2AALDH1A1LCK | |
| SCHEMBL29887527 | 0.72 | AR (0.63) | MAPTKDM4EMEN1PKMHTT | |
| SCHEMBL475069 | 0.72 | AR (0.63) | MAPTKDM4EMEN1PKMHTT | |
| SCHEMBL14137873 | 0.72 | NOS1 (0.53) | MAPTKDM4EMEN1PKMHTT | |
| Hydrochloric Acid SCHEMBL31173861 | 0.71 | AR (0.61) | MAPTKDM4EMEN1PKMHTT | |
| Hydrochloric Acid SCHEMBL6999702 | 0.71 | AR (0.61) | MAPTKDM4EMEN1PKMHTT | |
| SCHEMBL27925326 | 0.71 | TRPV1 (0.43) | MAPTKDM4EMEN1PKMHTT | |
| SCHEMBL651823 | 0.70 | ESR1 (0.42) | MAPTKDM4EMEN1PKMHTT | |
| Hydrochloric Acid SCHEMBL29176224 | 0.70 | NOS1 (0.52) | MAPTKDM4EMEN1PKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006135383-A2 | INDAZOLES | MYRIAD GENETICS, INC. (US) | 2006-12-21 | — | — | WO | disclosed |