Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 5/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NEK2 | P51955 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 4/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.43 |
| ▸ | WNT3A | P56704 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5823007 | 0.88 | MAPT (0.47) | MAPTKDM4EMEN1ALDH1A1HPGD | |
| SCHEMBL28922588 | 0.76 | LCK (0.35) | MAPTMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL14642595 | 0.75 | ROCK2 (0.53) | ROCK2ROCK1RAB9AMAPTKDM4E | |
| SCHEMBL1122014 | 0.75 | F2 (0.46) | RAB9AMAPTGAACTNNB1WNT3A | |
| SCHEMBL6816789 | 0.73 | ROCK2 (0.59) | ROCK2ROCK1RAB9AMEN1KMT2A | |
| SCHEMBL6083112 | 0.73 | AR (0.51) | MAPTKDM4EMEN1ALDH1A1HPGD | |
| SCHEMBL5799577 | 0.72 | AR (0.63) | ROCK2ROCK1RAB9AMAPTKDM4E | |
| SCHEMBL1419814 | 0.72 | AR (0.63) | ROCK2ROCK1RAB9AMAPTKDM4E | |
| SCHEMBL29949712 | 0.72 | AR (0.63) | ROCK2ROCK1RAB9AMAPTKDM4E | |
| SCHEMBL3105606 | 0.72 | ROCK2 (0.53) | ROCK2ROCK1RAB9AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006135383-A2 | INDAZOLES | MYRIAD GENETICS, INC. (US) | 2006-12-21 | — | — | WO | disclosed |