Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 6/20 | 0.71 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.71 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9458666 | 0.89 | GCGR (0.54) | GCGRMAPK14ALDH1A1HPGD | |
| SCHEMBL8498146 | 0.83 | GCGR (0.57) | GCGRMAPK14ALDH1A1HPGD | |
| SCHEMBL7981809 | 0.80 | PTGS2 (0.77) | GCGRMAPK14PTGS2 | |
| SCHEMBL11978812 | 0.79 | GCGR (0.54) | GCGRMAPK14PTGS2 | |
| SCHEMBL5311606 | 0.76 | CA2 (0.54) | PTGS2 | |
| SCHEMBL6195404 | 0.76 | SMN1; SMN2 (0.47) | GCGRMAPK14ALDH1A1HPGD | |
| SCHEMBL30726109 | 0.74 | GCGR (0.56) | GCGRMAPK14PTGS2 | |
| SCHEMBL17016711 | 0.72 | MAPK14 (0.54) | GCGRMAPK14PTGS2 | |
| SCHEMBL7982199 | 0.72 | PTGS2 (0.59) | GCGRMAPK14PTGS2 | |
| SCHEMBL7983759 | 0.71 | GCGR (0.53) | GCGRMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006110918-A1 | PYRROLE COMPOUNDS AND USES THEREOF | AMBIT BIOSCIENCES CORPORATION (US) | 2006-10-19 | — | — | WO | disclosed |