Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5823610 | 0.85 | PNMT (0.41) | PNMTNPC1RAB9APGRHTR2A | |
| SCHEMBL29606694 | 0.76 | PNMT (0.35) | PNMTNPC1RAB9A | |
| SCHEMBL21326206 | 0.74 | PNMT (0.37) | PNMTNPC1RAB9ACYP3A4HSD17B10 | |
| SCHEMBL2968923 | 0.74 | MAOA (0.35) | NPC1RAB9AHTR2AHTR2BSIGMAR1 | |
| SCHEMBL7602996 | 0.72 | PNMT (0.35) | PNMTNPC1RAB9APGRHTR7 | |
| SCHEMBL8857057 | 0.72 | PNMT (0.45) | PNMTNPC1RAB9A | |
| SCHEMBL8151832 | 0.72 | — | — | |
| SCHEMBL17024336 | 0.71 | PNMT (0.41) | PNMTNPC1RAB9APGRHTR2A | |
| SCHEMBL7612690 | 0.71 | PNMT (0.33) | PNMTNPC1RAB9A | |
| SCHEMBL7605924 | 0.71 | PNMT (0.44) | PNMTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0751143-B1 | Process for the preparation of carbon bridged dicyclopentadiene compounds | BASELL POLYOLEFINE GMBH (DE) | 2001-09-05 | — | — | EP | disclosed |
| EP-0751143-A2 | Process for the preparation of carbon bridged dicyclopentadiene compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-01-02 | — | — | EP | disclosed |