Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5824226 | 0.71 | F2 (0.43) | F2MEN1LMNAALDH1A1RAB9A | |
| SCHEMBL11037082 | 0.71 | FBP1 (0.30) | — | |
| SCHEMBL5731997 | 0.66 | MEN1 (0.43) | MEN1LMNAALDH1A1RAB9A | |
| SCHEMBL5731999 | 0.66 | MEN1 (0.43) | MEN1LMNAALDH1A1RAB9A | |
| SCHEMBL20625628 | 0.61 | F2 (0.36) | F2MEN1ALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL30271626 | 0.59 | F2 (0.38) | F2MEN1LMNAALDH1A1RAB9A | |
| SCHEMBL25215681 | 0.59 | F2 (0.41) | F2MEN1LMNAALDH1A1RAB9A | |
| SCHEMBL11367950 | 0.59 | F2 (0.44) | F2MEN1LMNAALDH1A1RAB9A | |
| SCHEMBL2651752 | 0.59 | ALDH1A1 (0.51) | F2MEN1LMNAALDH1A1RAB9A | |
| SCHEMBL30859024 | 0.58 | F2 (0.37) | F2MEN1LMNAALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664063-A1 | SUBSTITUTED PIPERAZINES OF AZEPINES, OXAZEPINES, AND THIAZEPINES | ELI LILLY AND COMPANY (US) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005026177-A1 | SUBSTITUTED PIPERAZINES OF AZEPINES, OXAZEPINES, AND THIAZEPINES | ELI LILLY AND COMPANY (US) | 2005-03-24 | — | — | WO | disclosed |