Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | DGKA | P23743 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.30 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.30 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6580192 | 0.80 | TSHR (0.47) | TSHRACACBCYP2C19ZDHHC20ZDHHC2 | |
| SCHEMBL660975 | 0.75 | TSHR (0.45) | TSHRACACBCYP2C19ZDHHC20ZDHHC2 | |
| SCHEMBL5207256 | 0.74 | TSHR (0.48) | TSHRACACBCYP2C19ZDHHC20ZDHHC2 | |
| SCHEMBL5382265 | 0.72 | MEN1 (0.54) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL18124154 | 0.71 | TSHR (0.50) | TSHRACACBCYP2C19ZDHHC20ZDHHC2 | |
| Glycerin SCHEMBL27971473 | 0.71 | TSHR (0.72) | TSHRMEN1KMT2ALMNAACACB | |
| SCHEMBL28257876 | 0.70 | TSHR (0.44) | TSHRACACBCYP2C19ZDHHC20ZDHHC2 | |
| SCHEMBL10487230 | 0.70 | TSHR (0.48) | TSHRACACBCYP2C19ZDHHC20ZDHHC2 | |
| SCHEMBL11316755 | 0.70 | TSHR (0.46) | TSHRACACBCYP2C19ZDHHC20ZDHHC2 | |
| SCHEMBL1303579 | 0.70 | ALDH1A1 (0.37) | TSHRACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113539-A1 | Crosslinked, water insoluble matrix; electrophoresis membranes | GE HEALTHCARE BIO-SCIENCES AB (SE) | 2005-05-26 | — | — | US | claimed |
| WO-2003055923-A1 | NOVEL MONOMERS USEFUL IN THE PREPARATION OF SEPARATION MATRICES | AMERSHAM BIOSCIENCES AB (SE) | 2003-07-10 | — | — | WO | claimed |
| US-7060776-B2 | Monomers useful in the preparation of separation matrices | GE HEALTHCARE BIO-SCIENCES AB (SE) | 2006-06-13 | — | — | US | disclosed |
| US-20050113539-A1 | Crosslinked, water insoluble matrix; electrophoresis membranes | GE HEALTHCARE BIO-SCIENCES AB (SE) | 2005-05-26 | — | — | US | disclosed |
| WO-2003055923-A1 | NOVEL MONOMERS USEFUL IN THE PREPARATION OF SEPARATION MATRICES | AMERSHAM BIOSCIENCES AB (SE) | 2003-07-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113539-A1 | Crosslinked, water insoluble matrix; electrophoresis membranes | H1-0, H1-4, H1-2 | TSHR 3304/4885KDM4E 943/4885DUSP3 4418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.