Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 2/20 | 0.49 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.48 |
| ▸ | GBA1 | P04062 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17968039 | 1.00 | ACHE (0.64) | ACHEKMT2ACYP2A13LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL4227174 | 0.98 | ACHE (0.62) | ACHEKMT2ACYP2A13LMNAALDH1A1 | |
| SCHEMBL8107673 | 0.90 | ACHE (0.73) | ACHEKMT2ACYP2A13LMNAALDH1A1 | |
| SCHEMBL6941873 | 0.90 | ACHE (0.73) | ACHEKMT2ACYP2A13LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL8786449 | 0.89 | ACHE (0.71) | ACHEKMT2ACYP2A13LMNAALDH1A1 | |
| SCHEMBL4222739 | 0.88 | ACHE (0.49) | ACHEKMT2ACYP2A13LMNAALDH1A1 | |
| SCHEMBL15084359 | 0.82 | ACHE (0.81) | ACHEKMT2ACYP2A13LMNAALDH1A1 | |
| SCHEMBL21460313 | 0.81 | KDM1A (0.47) | ACHEKMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL5824541 | 0.81 | CXCR4 (0.65) | KMT2ACYP2A13ALDH1A1CXCR4KDM4E | |
| SCHEMBL14344767 | 0.81 | ACHE (0.64) | ACHEKMT2ACYP2A13LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7135466-B2 | Quinoline and quinazoline derivatives and drugs containing the same | KIRIN BEER KABUSHIKI KAISHA (JP) | 2006-11-14 | — | — | US | disclosed |
| US-20060211717-A1 | Quinoline and quinazoline derivatives and drugs containing the same | KIRIN BEER KABUSHIKI KAISHA (JP) | 2006-09-21 | — | — | US | disclosed |
| US-20040132727-A1 | Quinoline and quinazoline derivatives and drugs containing the same | KIRIN HOLDINGS KABUSHIKI KAISHA (JP) | 2004-07-08 | — | — | US | disclosed |
| EP-1243582-A1 | QUINOLINE AND QUINAZOLINE DERIVATIVES AND DRUGS CONTAINING THE SAME | KIRIN BEER KABUSHIKI KAISHA (JP) | 2002-09-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211717-A1 | Quinoline and quinazoline derivatives and drugs containing the same | PDGFRA, PDGFRB, PDGFA | ACHE 3138/4885KMT2A 2022/4885CYP2A13 3816/4885 |
| US-20040132727-A1 | Quinoline and quinazoline derivatives and drugs containing the same | PDGFRA, PDGFRB, PDGFA | ACHE 3471/4885KMT2A 2006/4885CYP2A13 3429/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.