Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 7/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | CYP2A13 | Q16696 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31669240 | 1.00 | CXCR4 (0.65) | CXCR4ALDH1A1ATMSIGMAR1CYP2A13 | |
| Hydrochloric Acid SCHEMBL28987734 | 0.98 | CXCR4 (0.63) | CXCR4ALDH1A1ATMSIGMAR1CYP2A13 | |
| SCHEMBL25231483 | 0.91 | CXCR4 (0.57) | CXCR4ALDH1A1ATMSIGMAR1CYP2A13 | |
| SCHEMBL25274515 | 0.91 | CXCR4 (0.57) | CXCR4ALDH1A1ATMSIGMAR1CYP2A13 | |
| SCHEMBL6945977 | 0.90 | CXCR4 (0.73) | CXCR4ALDH1A1ATMSIGMAR1CYP2A13 | |
| Hydrochloric Acid SCHEMBL11533303 | 0.89 | CXCR4 (0.71) | CXCR4ALDH1A1ATMSIGMAR1CYP2A13 | |
| SCHEMBL2734472 | 0.82 | CYP2A13 (0.51) | CXCR4ALDH1A1SIGMAR1CYP2A13KDM4E | |
| SCHEMBL17968039 | 0.81 | ACHE (0.64) | CXCR4ALDH1A1SIGMAR1CYP2A13KDM4E | |
| SCHEMBL23507326 | 0.81 | CXCR4 (0.60) | CXCR4ALDH1A1ATMSIGMAR1CYP2A13 | |
| SCHEMBL5824435 | 0.81 | ACHE (0.64) | CXCR4ALDH1A1SIGMAR1CYP2A13KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7135466-B2 | Quinoline and quinazoline derivatives and drugs containing the same | KIRIN BEER KABUSHIKI KAISHA (JP) | 2006-11-14 | — | — | US | disclosed |
| US-20060211717-A1 | Quinoline and quinazoline derivatives and drugs containing the same | KIRIN BEER KABUSHIKI KAISHA (JP) | 2006-09-21 | — | — | US | disclosed |
| US-20040132727-A1 | Quinoline and quinazoline derivatives and drugs containing the same | KIRIN HOLDINGS KABUSHIKI KAISHA (JP) | 2004-07-08 | — | — | US | disclosed |
| EP-1243582-A1 | QUINOLINE AND QUINAZOLINE DERIVATIVES AND DRUGS CONTAINING THE SAME | KIRIN BEER KABUSHIKI KAISHA (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-4197243-A | ANTIPSYCHOTICS, STRONG CNS DEPRESSANTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1980-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211717-A1 | Quinoline and quinazoline derivatives and drugs containing the same | PDGFRA, PDGFRB, PDGFA | CXCR4 275/4885ALDH1A1 2003/4885ATM 412/4885 |
| US-20040132727-A1 | Quinoline and quinazoline derivatives and drugs containing the same | PDGFRA, PDGFRB, PDGFA | CXCR4 207/4885ALDH1A1 2059/4885ATM 504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.