Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5826055 | 0.83 | CES2 (0.33) | CES1CES2ALDH1A1 | |
| SCHEMBL22366928 | 0.81 | HSD11B1 (0.36) | P2RX7HSD11B1PTGS2SLC22A12CES1 | |
| SCHEMBL27455107 | 0.79 | CES2 (0.41) | CES1CES2ALDH1A1 | |
| SCHEMBL4547921 | 0.79 | P2RX7 (0.42) | P2RX7HSD11B1PTGS2SLC22A12CES1 | |
| SCHEMBL30705291 | 0.79 | P2RX7 (0.42) | P2RX7HSD11B1PTGS2SLC22A12CES1 | |
| SCHEMBL4083407 | 0.77 | P2RX7 (0.45) | P2RX7CES1CA2KDM4ESMN1; SMN2 | |
| SCHEMBL27801187 | 0.76 | P2RX7 (0.51) | P2RX7HSD11B1PTGS2SLC22A12CES1 | |
| SCHEMBL26620983 | 0.76 | P2RX7 (0.40) | P2RX7HSD11B1SLC22A12SMN1; SMN2IDO1 | |
| SCHEMBL14120994 | 0.76 | P2RX7 (0.40) | P2RX7HSD11B1SLC22A12SMN1; SMN2IDO1 | |
| SCHEMBL19697140 | 0.75 | HSD11B1 (0.39) | P2RX7HSD11B1PTGS2SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2006282511-A | 2-TRIFLUOROMETHYL-6-FLUOROBENZAL CHLORIDE AND PRODUCTION METHOD OF IT AND ITS DERIVATIVE | CENTRAL GLASS CO LTD | 2006-10-19 | — | — | JP | disclosed |
| JP-2006213630-A | METHOD FOR PRODUCING 2-TRIFLUOROMETHYL-6-FLUOROBENZALDEHYDE AND ITS DERIVATIVE | CENTRAL GLASS CO LTD | 2006-08-17 | — | — | JP | disclosed |