SCHEMBL5826255

SCHEMBL5826255

CC12CC3(C)CC(C(=O)O)(C1)CC(C14CC5(C)CC(C)(CC(c6ccc(O)cc6)(C5)C1)C4)(C2)C3

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.33
APP P05067 2/20 0.32
CYP2C19 P33261 2/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP3A4 P08684 1/20 0.32
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
MMP2 P08253 1/20 0.31
MMP9 P14780 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3840705 0.86 ESR1 (0.39) CYP3A4ESR1ESR2MMP2MMP9
SCHEMBL19148484 0.79 MEN1 (0.39) PKM
SCHEMBL344102 0.78 ESR2 (0.42) CYP3A4ESR1ESR2MMP2MMP9
SCHEMBL2746399 0.78 PKM (0.50) PKM
SCHEMBL2747623 0.77 RXRA (0.43) CYP3A4
Hydrochloric Acid SCHEMBL2710449 0.76 PKM (0.48) PKM
Hydrochloric Acid SCHEMBL5000662 0.76 PKM (0.48) PKM
SCHEMBL4059740 0.72 PNMT (0.38) MMP2MMP9
SCHEMBL3842319 0.72 ESR1 (0.44) CYP3A4ESR1ESR2MMP2MMP9
SCHEMBL301039 0.70 PKM (0.59) PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2006342093-A BIADAMANTANE DERIVATIVE DAICEL CHEM IND LTD 2006-12-21 JP disclosed