Aziridine

Aziridine

SCHEMBL5828076

C1CN1.C=C(C)C(=O)OCO

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.47
ALDH1A1 P00352 2/20 0.46
THRB P10828 1/20 0.44
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
HTT P42858 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL36180 0.89
SCHEMBL30365675 0.89 TSHR (0.56) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL453052 0.89 TSHR (0.56) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL460181 0.86 TSHR (0.50) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL14054416 0.86 TSHR (0.50) TSHRALDH1A1THRBPOLBAPEX1
Methyl Alcohol SCHEMBL8414271 0.86 TSHR (0.54) TSHRALDH1A1THRBPOLBAPEX1
Ammonia Solution, Strong SCHEMBL28243650 0.86
Propane SCHEMBL15475973 0.84 THRB (0.54) TSHRALDH1A1THRBPOLBAPEX1
Propane SCHEMBL3445673 0.84 THRB (0.54) TSHRALDH1A1THRBPOLBAPEX1
Aziridine SCHEMBL19714788 0.83 THRB (0.50) TSHRALDH1A1THRBPOLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1499667-B1 COATING COMPOSITION FOR MULTIPLE HYDROPHILIC APPLICATIONS HYDROMER INC (US) 2013-08-14 EP claimed
US-20060270776-A1 A MATTE FINISH COMPOSITION HARRIS RESEARCH, INC. (US) 2006-11-30 US claimed
US-7008979-B2 Coating composition for multiple hydrophilic applications HYDROMER, INC. (US) 2006-03-07 US claimed
EP-1499667-A4 COATING COMPOSITION FOR MULTIPLE HYDROPHILIC APPLICATIONS HYDROMER INC (US) 2005-12-07 EP claimed
EP-1499667-A1 COATING COMPOSITION FOR MULTIPLE HYDROPHILIC APPLICATIONS Hydromer, Inc. (US) 2005-01-26 EP claimed
WO-2003093357-A1 COATING COMPOSITION FOR MULTIPLE HYDROPHILIC APPLICATIONS HYDROMER, INC. (US) 2003-11-13 WO claimed
US-20030203991-A1 Coating composition for multiple hydrophilic applications HYDROMER, INC. 2003-10-30 US claimed
US-10241237-B2 Anti-fog coating comprising aqueous polymeric dispersion, crosslinker and surfactant 3M INNOVATIVE PROPERTIES COMPANY (US) 2019-03-26 US disclosed
CN-104053731-B Comprise the anti-fog coating of aqueous polymer dispersion, cross-linking agent and surfactant 3M创新有限公司 2016-10-26 CN disclosed
EP-2791257-B1 ANTI-FOG COATING COMPRISING AQUEOUS POLYMERIC DISPERSION, CROSSLINKER AND ACID OR SALT OF POLYALKYLENE OXIDE 3M INNOVATIVE PROPERTIES CO (US) 2016-04-13 EP disclosed
US-20150118501-A1 ANTI-FOG COATING COMPRISING AQUEOUS POLYMERIC DISPERSION, CROSSLINKER & ACID OR SALT OF POLYALKYLENE OXIDE 3M INNOVATIVE PROPERTIES COMPANY 2015-04-30 US disclosed
US-20140335360-A1 ANTI-FOG COATING COMPRISING AQUEOUS POLYMERIC DISPERSION, CROSSLINKER & SURFACTANT 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-11-13 US disclosed
EP-2791257-A1 ANTI-FOG COATING COMPRISING AQUEOUS POLYMERIC DISPERSION, CROSSLINKER&ACID OR SALT OF POLYALKYLENE OXIDE 3M Innovative Properties Company (US) 2014-10-22 EP disclosed
EP-1499667-A4 COATING COMPOSITION FOR MULTIPLE HYDROPHILIC APPLICATIONS HYDROMER INC (US) 2005-12-07 EP disclosed
EP-1499667-A1 COATING COMPOSITION FOR MULTIPLE HYDROPHILIC APPLICATIONS Hydromer, Inc. (US) 2005-01-26 EP disclosed
WO-2003093357-A1 COATING COMPOSITION FOR MULTIPLE HYDROPHILIC APPLICATIONS HYDROMER, INC. (US) 2003-11-13 WO disclosed
US-20030203991-A1 Coating composition for multiple hydrophilic applications HYDROMER, INC. 2003-10-30 US disclosed
US-4916045-A Printing plates, relief images, photoresists BASF AKTIENGESELLSCHAFT (DE) 1990-04-10 US disclosed
US-4900795-A PHOTOPOLMERIZABLE POLYMER COMPRISING ETHYLENE, (METH)ACRYLIC ACID AND VINYL OR ACRYLATE MONOMER NEUTRALIZED BY A CYCLIC AMINE OR HYDROXY-CONTAINING AMINE; PHOTORESISTS; PRINTING PLATES; OZONE RESISTANCE; ELONGATION; TENSILE STRENGTH BASF AKTIENGESELLSCHAFT (DE) 1990-02-13 US disclosed
US-4762892-A ETHYLENE-ACRYLIC OR METHACRYLIC ACID-ALKYL ACRYLATE MODIFIED TO CONTAIN UNSATURATED SIDE CHAINS BASF AKTIENGESELLSCHAFT (DE) 1988-08-09 US disclosed