Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.35 |
| ▸ | WDR5 | P61964 | 1/20 | 0.35 |
| ▸ | TYMP | P19971 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27300614 | 0.90 | HSD17B10 (0.41) | HPGDHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL3955070 | 0.88 | HSD17B10 (0.47) | HPGDHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL18315347 | 0.82 | GPR84 (0.38) | HPGDHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL16384836 | 0.81 | HPGD (0.57) | HPGDHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL8053651 | 0.80 | HPGD (0.39) | HPGDHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL9861267 | 0.79 | HPGD (0.33) | HPGDHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL648242 | 0.77 | HSD17B10 (0.42) | HPGDHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL28120414 | 0.76 | HSD11B1 (0.47) | HPGDHSD17B10DNMT1ALDH1A1KDM4E | |
| SCHEMBL7776439 | 0.76 | CYP1A2 (0.38) | HPGDHSD17B10CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL5509954 | 0.75 | KCNJ11 (0.44) | HPGDHSD17B10CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8053482-A | — | — | None | — | — | JP | disclosed |
| US-7102034-B2 | Process for preparing sulfonated arylphosphines | CELANESE CHEMICALS EUROPE GMBH (DE) | 2006-09-05 | — | — | US | disclosed |
| US-5565398-A | Sulfonated 2,2'-bis (Diphenylphosphinomethyl)-1,1'-binaphthalenes, process for their preparation and their use in a process for the hydroformylation of olefinically unsaturated compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-10-15 | — | — | US | disclosed |
| JP-H0853482-A | PALLADIUM CATALYST CONTAINING SULFONATED BISPHOSPHINE AS LIGAND, ITS PREPARATION AND ITS USE IN CARBONYLATION REACTION | HOECHST AG | 1996-02-27 | — | — | JP | disclosed |
| US-5481045-A | Sulfonated 2,2'-bis (diphenylphosphinomethyl)-1,1'-binaphthalenes, process for their preparation and their use in a process for the hydroformylation of olefinically unsaturated compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-01-02 | — | — | US | disclosed |
| US-5347045-A | Sulfonated 2,2'-bis (diphenylphosphinomethyl)-1,1'-binaphthalenes, process for their preparation and their use in a process for the hydroformylation of olefinically unsaturated compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-09-13 | — | — | US | disclosed |