Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.52 |
| ▸ | EGLN3 | Q9H6Z9 | 2/20 | 0.36 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 6/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.31 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL9725171 | 0.90 | ALDH1A1 (0.59) | ALDH1A1FKBP5EGLN3TBXAS1BCHE | |
| Adipic Acid SCHEMBL11235203 | 0.86 | ALDH1A1 (0.54) | ALDH1A1FKBP5TBXAS1GPR84FFAR1 | |
| Glycolic Acid SCHEMBL31731101 | 0.85 | ALDH1A1 (0.59) | ALDH1A1FKBP5EGLN3 | |
| Sebacic Acid SCHEMBL10578918 | 0.84 | ALDH1A1 (0.52) | ALDH1A1FKBP5TBXAS1GPR84FFAR1 | |
| Sebacic Acid SCHEMBL10578909 | 0.84 | ALDH1A1 (0.52) | ALDH1A1FKBP5TBXAS1GPR84FFAR1 | |
| Imidazole SCHEMBL28533199 | 0.84 | ALDH1A1 (0.52) | ALDH1A1FKBP5TBXAS1GPR84FFAR1 | |
| Butyric Acid SCHEMBL21632810 | 0.82 | ALDH1A1 (0.50) | ALDH1A1FKBP5EGLN3GPR84FFAR1 | |
| Imidazole SCHEMBL28161392 | 0.82 | ALDH1A1 (0.54) | ALDH1A1FKBP5 | |
| Malonic Acid SCHEMBL14695335 | 0.81 | ALDH1A1 (0.59) | ALDH1A1FKBP5EGLN3 | |
| Malonic Acid SCHEMBL28601856 | 0.81 | ALDH1A1 (0.59) | ALDH1A1FKBP5EGLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39333-E1 | Process for the preparation of 5-hydroxy-3-oxopentanoic acid derivatives | KANEKA CORPORATION (JP) | 2006-10-10 | — | — | US | disclosed |
| EP-1104750-B1 | PROCESSES FOR THE PREPARATION OF 5-HYDROXY-3-OXOPENTANOIC ACID DERIVATIVES | KANEKA CORP (JP) | 2004-04-14 | — | — | EP | disclosed |
| US-6340767-B1 | REACTION OF LITHIUM AMIDE WITH ACETIC ACID ESTER AND HYDROXY PROPIONIC ACID | KANEKA CORPORATION (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-1104750-A1 | PROCESSES FOR THE PREPARATION OF 5-HYDROXY-3-OXOPENTANOIC ACID DERIVATIVES | KANEKA CORPORATION (JP) | 2001-06-06 | — | — | EP | disclosed |