Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 10/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MLYCD | O95822 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5830139 | 0.97 | HPGD (0.50) | HPGDALDH1A1CA12CA1CA2 | |
| SCHEMBL5830651 | 0.84 | PLA2G7 (0.41) | HPGDALDH1A1CA12CA1CA2 | |
| Terephthalamide SCHEMBL1160127 | 0.77 | HPGD (0.76) | HPGDALDH1A1CA12CA1CA2 | |
| SCHEMBL472215 | 0.77 | HPGD (0.76) | HPGDALDH1A1CA12CA1CA2 | |
| SCHEMBL5694406 | 0.77 | HPGD (0.76) | HPGDALDH1A1CA12CA1CA2 | |
| SCHEMBL7304754 | 0.77 | PARP10 (0.41) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL5830250 | 0.76 | GAA (0.58) | HPGDALDH1A1CA12CA1CA2 | |
| SCHEMBL367513 | 0.75 | HPGD (0.80) | HPGDALDH1A1CA12CA1CA2 | |
| SCHEMBL1160398 | 0.75 | HPGD (0.80) | HPGDALDH1A1CA12CA1CA2 | |
| SCHEMBL367607 | 0.75 | HPGD (0.80) | HPGDALDH1A1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7030141-B2 | Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade | WARNER-LAMBERT COMPANY LLC | 2006-04-18 | — | — | US | disclosed |