SCHEMBL3426355

SCHEMBL3426355

CCC(OCCOC)C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.37
CYP4F2 P78329 3/20 0.35
CYP4A11 Q02928 3/20 0.35
ALDH1A1 P00352 1/20 0.34
DDAH1 O94760 1/20 0.33
CPB2 Q96IY4 3/20 0.31
CPB1 P15086 2/20 0.31
TSHR P16473 1/20 0.31
CA2 P00918 1/20 0.30
MAPK1 P28482 1/20 0.30
PPARA Q07869 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7653761 0.94 SMN1; SMN2 (0.34) SMN1; SMN2CYP4F2CYP4A11ALDH1A1DDAH1
SCHEMBL5830472 0.94 SMN1; SMN2 (0.34) SMN1; SMN2CYP4F2CYP4A11ALDH1A1DDAH1
SCHEMBL445610 0.84 SMN1; SMN2 (0.40) SMN1; SMN2CYP4F2CYP4A11CPB2CPB1
SCHEMBL14996288 0.84 SMN1; SMN2 (0.40) SMN1; SMN2CYP4F2CYP4A11CPB2CPB1
SCHEMBL7647468 0.83 PPARG (0.43) ALDH1A1DDAH1CPB2CPB1TSHR
SCHEMBL7367907 0.81 DDAH1 (0.33) DDAH1CA2
SCHEMBL16246663 0.81 ALDH1A1 (0.43) SMN1; SMN2CYP4F2CYP4A11ALDH1A1CPB2
SCHEMBL27525591 0.81 ALDH1A1 (0.33) ALDH1A1DDAH1
SCHEMBL3204334 0.80 SMN1; SMN2 (0.33) SMN1; SMN2CYP4F2CYP4A11PPARA
SCHEMBL7647510 0.80 CA2 (0.42) DDAH1CPB2CPB1CA2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116437913-A Pharmaceutical compounds for treating complement-mediated disorders 艾其林医药公司 2023-07-14 CN disclosed
US-20220185785-A1 INHIBITORS OF CD40-CD154 BINDING TONIX Pharmaceuticals Holding Corp (US) 2022-06-16 US disclosed
CN-114173772-A Inhibitors of CD40-CD154 binding 托尼克斯医药控股公司 2022-03-11 CN disclosed
EP-3952853-A1 INHIBITORS OF CD40-CD154 BINDING Tonix Pharmaceuticals Holding Corp. (US) 2022-02-16 EP disclosed
WO-2020210831-A1 INHIBITORS OF CD40-CD154 BINDING TONIX Pharmaceuticals Holding Corp (US) 2020-10-15 WO disclosed
US-7683196-B2 Isocyanate-free primer composition for glass and glass ceramics SIKA TECHNOLOGY AG (CH) 2010-03-23 US disclosed
US-20070043196-A1 Isocyanate-free primer composition for glass and glass ceramics SIKA TECHNOLOGY AG (CH) 2007-02-22 US disclosed
US-6350795-B1 ACOUSTIC PHASE-CHANGE CONDUCTIVE INK CONTAINING LOW MOLECULAR WEIGHT OXYALKYLENE SEGMENTS COMPLEXED WITH UREA DERIVATIVES XEROX CORPORATION 2002-02-26 US disclosed
US-6096125-A Ink compositions XEROX CORPORATION (US) 2000-08-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220185785-A1 INHIBITORS OF CD40-CD154 BINDING CD40LG, CD40, CD4 SMN1; SMN2 3984/4885CYP4F2 810/4885CYP4A11 229/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.