Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 8/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | EDNRB | P24530 | 2/20 | 0.43 |
| ▸ | EDNRA | P25101 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.43 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.41 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.41 |
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.41 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6623494 | 0.86 | MEN1 (0.51) | KDM1AHSD11B1MEN1KMT2ALMNA | |
| SCHEMBL5391755 | 0.83 | MEN1 (0.60) | KDM1AHSD11B1MEN1KMT2ALMNA | |
| SCHEMBL6622547 | 0.82 | KMT2A (0.47) | KDM1AHSD11B1MEN1KMT2ALMNA | |
| SCHEMBL5389359 | 0.81 | KDM1A (0.52) | KDM1AHSD11B1MEN1KMT2ALMNA | |
| SCHEMBL5830734 | 0.81 | HSD11B1 (0.46) | KDM1AHSD11B1EDNRBEDNRAHSD17B1 | |
| SCHEMBL2763006 | 0.81 | KDM1A (0.61) | KDM1AHSD11B1MEN1KMT2AHSD17B1 | |
| SCHEMBL6690238 | 0.79 | SLC40A1 (0.46) | HSD11B1EDNRBEDNRASLC40A1 | |
| SCHEMBL5831833 | 0.78 | HSD11B1 (0.51) | KDM1AHSD11B1MEN1KMT2ALMNA | |
| SCHEMBL5398543 | 0.77 | SLC40A1 (0.54) | KDM1AHSD11B1EDNRBEDNRAHSD17B1 | |
| SCHEMBL6611897 | 0.77 | ACLY (0.44) | HSD11B1EDNRBEDNRASLC40A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030130258-A1 | Antidiabetic agents; liver disorders; cardiovascular disorders; dietetics | BIOVITRUM AB (SE) | 2003-07-10 | — | — | US | claimed |
| US-7074788-B2 | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 | BIOVITRUM AB (SE) | 2006-07-11 | — | — | US | disclosed |
| US-20030130258-A1 | Antidiabetic agents; liver disorders; cardiovascular disorders; dietetics | BIOVITRUM AB (SE) | 2003-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130258-A1 | Antidiabetic agents; liver disorders; cardiovascular disorders; dietetics | CPT1A, HSD11B1, CES1 | KDM1A 1842/4885HSD11B1 2/4885MEN1 903/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.