Glycine

Glycine

SCHEMBL583139

NCC(=O)[O-].O=C([O-])[O-].[K+].[K+].[K+]

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D

The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA4 P22748 5/20 0.44
GLRA1 P23415 1/20 0.44
SLC6A9 P48067 1/20 0.44
OR51E2 Q9H255 1/20 0.44
MEN1 O00255 1/20 0.41
LDHA P00338 1/20 0.41
BLM P54132 1/20 0.41
KMT2A Q03164 1/20 0.41
FAHD1 Q6P587 1/20 0.40
CASP1 P29466 1/20 0.39
CA2 P00918 2/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA9 Q16790 1/20 0.38
FFAR3 O14843 2/20 0.35
HDAC3 O15379 2/20 0.35
HDAC1 Q13547 2/20 0.35
HDAC2 Q92769 2/20 0.35
HDAC8 Q9BY41 2/20 0.35
GABRR1 P24046 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycine SCHEMBL22948 0.96
Glycine SCHEMBL5712834 0.96 CA4 (0.47) CA4GLRA1SLC6A9OR51E2MEN1
Glycine SCHEMBL6237271 0.92 CA4 (0.44) CA4GLRA1SLC6A9OR51E2MEN1
Glycine SCHEMBL28453127 0.92
Glycine SCHEMBL6237182 0.92 CA4 (0.44) CA4GLRA1SLC6A9OR51E2MEN1
Glycine SCHEMBL16601 0.92 CA4 (0.50) CA4GLRA1SLC6A9OR51E2MEN1
Glycine SCHEMBL28665132 0.92 CA4 (0.50) CA4GLRA1SLC6A9OR51E2MEN1
Glycine SCHEMBL2586655 0.92 CA4 (0.44) CA4GLRA1SLC6A9OR51E2MEN1
Glycine SCHEMBL2916896 0.92 CA4 (0.50) CA4GLRA1SLC6A9OR51E2MEN1
Glycine SCHEMBL8056321 0.90 GLRA1 (0.44) CA4GLRA1SLC6A9OR51E2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4496874-A1 A SOLID HARD SURFACE CLEANING COMPOSITION Unilever IP Holdings B.V. (NL) 2025-01-29 EP claimed
CN-118974224-A Solid hard surface cleaning compositions 联合利华知识产权控股有限公司 2024-11-15 CN claimed
WO-2023180053-A1 A SOLID HARD SURFACE CLEANING COMPOSITION UNILEVER IP HOLDINGS B.V. (NL) 2023-09-28 WO claimed
CN-111803442-B Stabilizer for improving bioavailability of ammonium glycyrrhetate S liquid dosage form and application thereof 广州一品红制药有限公司 2022-06-14 CN claimed
CN-111803442-A Stabilizer for improving bioavailability of ammonium glycyrrhetate S liquid dosage form and application thereof 广州一品红制药有限公司 2020-10-23 CN claimed
US-6077536-A AMOXYCILLIN HYDRATE AND EFFERVESCENT ACID AND BASE COUPLE BEECHAM GROUP PLC (GB) 2000-06-20 US claimed
US-6051254-A AMOXYCILLIN HYDRATE, AN EFFERVESCENT COUPLE, BETA.-LACTAMASE INHIBITOR; THE EFFERVESCENT COUPLE COMPRISES AN ACID COMPONENT AND AN ALKALINE COMPONENT SMITHKLINE BEECHAM PLC (GB) 2000-04-18 US claimed
US-20260085255-A1 LAUNDRY COMPOSITION CONOPCO, INC., D/B/A UNILEVER (US) 2026-03-26 US disclosed
US-20260085254-A1 LAUNDRY COMPOSITION CONOPCO, INC., D/B/A UNILEVER (US) 2026-03-26 US disclosed
EP-4663738-A1 LAUNDRY UNIT DOSE PRODUCT Unilever IP Holdings B.V. (NL) 2025-12-17 EP disclosed
EP-4663737-A1 LAUNDRY UNIT DOSE PRODUCT Unilever IP Holdings B.V. (NL) 2025-12-17 EP disclosed
EP-4658745-A1 LAUNDRY COMPOSITION Unilever IP Holdings B.V. (NL) 2025-12-10 EP disclosed
EP-4584354-A1 LAUNDRY COMPOSITION Unilever IP Holdings B.V. (NL) 2025-07-16 EP disclosed
US-20160220481-A1 Low-Sodium Effervescent Pharmaceutical Formulations EFFRX PHARMACEUTICALS SA (CH) 2016-08-04 US disclosed
EP-3046549-A1 LOW-SODIUM EFFERVESCENT PHARMACEUTICAL FORMULATIONS Effrx Pharmaceuticals SA (CH) 2016-07-27 EP disclosed
WO-2015040460-A1 LOW-SODIUM EFFERVESCENT PHARMACEUTICAL FORMULATIONS EFFRX PHARMACEUTICALS SA (CH) 2015-03-26 WO disclosed
EP-1931222-B1 GELLING COMPOSITIONS AND METHODS FMC BIOPOLYMER AS (NO) 2012-02-15 EP disclosed
EP-1931222-A2 GELLING COMPOSITIONS AND METHODS FMC Biopolymer AS (NO) 2008-06-18 EP disclosed
US-20070087038-A1 GELLING COMPOSITIONS AND METHODS FMC BIOPOLYMER AS (NO) 2007-04-19 US disclosed
WO-2007039294-A2 GELLING COMPOSITIONS AND METHODS FMC BIOPOLYMER AS (NO) 2007-04-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260085255-A1 LAUNDRY COMPOSITION MGAM, GYS2, GALK1 CA4 148/4885GLRA1 3842/4885SLC6A9 807/4885
US-20260085254-A1 LAUNDRY COMPOSITION MGAM, TREH, GALK1 CA4 82/4885GLRA1 3148/4885SLC6A9 772/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.