Glycine

Glycine

SCHEMBL583141

NCC(=O)O.O=C(O)O.[KH]

nearest known ligand 0.83

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D

The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLRA1 P23415 1/20 0.83
SLC6A9 P48067 1/20 0.83
OR51E2 Q9H255 1/20 0.83
GABRR1 P24046 4/20 0.47
LMNA P02545 5/20 0.42
TSHR P16473 4/20 0.42
THRB P10828 3/20 0.42
BLM P54132 2/20 0.42
KMT2A Q03164 2/20 0.42
NPSR1 Q6W5P4 2/20 0.42
GABRR3 A8MPY1 1/20 0.42
GABRP O00591 1/20 0.42
GABRD O14764 1/20 0.42
HDAC3 O15379 1/20 0.42
GABBR2 O75899 1/20 0.42
CYP1A2 P05177 1/20 0.42
GABRA1 P14867 1/20 0.42
GABRB1 P18505 1/20 0.42
GABRG2 P18507 1/20 0.42
GABRB3 P28472 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycine SCHEMBL22949 0.96
Glycine SCHEMBL219254 0.96
Glycine SCHEMBL4274286 0.96 GLRA1 (0.91) GLRA1SLC6A9OR51E2GABRR1LMNA
Glycine SCHEMBL5712832 0.96
Glycine SCHEMBL8608021 0.96 GLRA1 (0.91) GLRA1SLC6A9OR51E2GABRR1LMNA
Glycine SCHEMBL2150066 0.92
Glycine SCHEMBL9474283 0.92 GLRA1 (0.83) GLRA1SLC6A9OR51E2GABRR1LMNA
Glycine SCHEMBL29168877 0.92
Glycine SCHEMBL2586660 0.92 GLRA1 (0.83) GLRA1SLC6A9OR51E2GABRR1LMNA
Glycine SCHEMBL28665130 0.92

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4496874-A1 A SOLID HARD SURFACE CLEANING COMPOSITION Unilever IP Holdings B.V. (NL) 2025-01-29 EP claimed
CN-118974224-A Solid hard surface cleaning compositions 联合利华知识产权控股有限公司 2024-11-15 CN claimed
WO-2023180053-A1 A SOLID HARD SURFACE CLEANING COMPOSITION UNILEVER IP HOLDINGS B.V. (NL) 2023-09-28 WO claimed
CN-111803442-B Stabilizer for improving bioavailability of ammonium glycyrrhetate S liquid dosage form and application thereof 广州一品红制药有限公司 2022-06-14 CN claimed
CN-111803442-A Stabilizer for improving bioavailability of ammonium glycyrrhetate S liquid dosage form and application thereof 广州一品红制药有限公司 2020-10-23 CN claimed
US-6077536-A AMOXYCILLIN HYDRATE AND EFFERVESCENT ACID AND BASE COUPLE BEECHAM GROUP PLC (GB) 2000-06-20 US claimed
US-6051254-A AMOXYCILLIN HYDRATE, AN EFFERVESCENT COUPLE, BETA.-LACTAMASE INHIBITOR; THE EFFERVESCENT COUPLE COMPRISES AN ACID COMPONENT AND AN ALKALINE COMPONENT SMITHKLINE BEECHAM PLC (GB) 2000-04-18 US claimed
US-20260085254-A1 LAUNDRY COMPOSITION CONOPCO, INC., D/B/A UNILEVER (US) 2026-03-26 US disclosed
US-20260085255-A1 LAUNDRY COMPOSITION CONOPCO, INC., D/B/A UNILEVER (US) 2026-03-26 US disclosed
EP-4663737-A1 LAUNDRY UNIT DOSE PRODUCT Unilever IP Holdings B.V. (NL) 2025-12-17 EP disclosed
EP-4663738-A1 LAUNDRY UNIT DOSE PRODUCT Unilever IP Holdings B.V. (NL) 2025-12-17 EP disclosed
EP-4658745-A1 LAUNDRY COMPOSITION Unilever IP Holdings B.V. (NL) 2025-12-10 EP disclosed
EP-4584354-A1 LAUNDRY COMPOSITION Unilever IP Holdings B.V. (NL) 2025-07-16 EP disclosed
US-20160220481-A1 Low-Sodium Effervescent Pharmaceutical Formulations EFFRX PHARMACEUTICALS SA (CH) 2016-08-04 US disclosed
EP-3046549-A1 LOW-SODIUM EFFERVESCENT PHARMACEUTICAL FORMULATIONS Effrx Pharmaceuticals SA (CH) 2016-07-27 EP disclosed
WO-2015040460-A1 LOW-SODIUM EFFERVESCENT PHARMACEUTICAL FORMULATIONS EFFRX PHARMACEUTICALS SA (CH) 2015-03-26 WO disclosed
EP-1931222-B1 GELLING COMPOSITIONS AND METHODS FMC BIOPOLYMER AS (NO) 2012-02-15 EP disclosed
EP-1931222-A2 GELLING COMPOSITIONS AND METHODS FMC Biopolymer AS (NO) 2008-06-18 EP disclosed
US-20070087038-A1 GELLING COMPOSITIONS AND METHODS FMC BIOPOLYMER AS (NO) 2007-04-19 US disclosed
WO-2007039294-A2 GELLING COMPOSITIONS AND METHODS FMC BIOPOLYMER AS (NO) 2007-04-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260085255-A1 LAUNDRY COMPOSITION MGAM, GYS2, GALK1 GLRA1 3842/4885SLC6A9 807/4885OR51E2 4699/4885
US-20260085254-A1 LAUNDRY COMPOSITION MGAM, TREH, GALK1 GLRA1 3148/4885SLC6A9 772/4885OR51E2 4607/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.